Issues
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Cover image
Cover Image
Cover: A honey bee (Apis mellifera) forager collecting nectar from an aloe flower in Tempe, Arizona. Worker honey bees exhibit complex, age-based division of labor where young workers remain within the nest, while older workers leave the nest to collect nectar and pollen to feed their nestmates. Scofield and Amdam (jeb247777) measured metabolic changes in worker fat body, the insect tissue filling the function of mammalian liver and adipose tissue. As workers age and become foragers, they suppress their capacity to synthesize lipids. Young workers deprived of dietary protein develop low, forager-like lipid synthesis capacity. Photo credit: Sebastian Scofield.
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INSIDE JEB
PERSPECTIVE
Big data and experimental biology: the complementary roles of hypothesis-led and blue skies research
Summary: The scientific method, with its strict emphasis on hypothesis testing, can sometimes feel limiting when asking open questions (‘how? why?’). Can ‘big data’ offer a solution?
SHORT COMMUNICATION
There is no limitation for CO2 excretion across the lung in exercising American alligators (Alligator mississippiensis)
Summary: The respiratory system of American alligators is well equipped to effectively eliminate CO2 during intense physical activity, maintaining stable arterial PCO2 levels without any signs of limitations in pulmonary CO2 diffusion.
THEORY & MODELLING
A new biomechanical model of the mammal jaw based on load path analysis
Summary: Load path analysis of a mammalian mandible allows precise mapping of force transfer routes through the cortical bone. This novel application of an engineering method offers biomechanical insight into skeletal form–function relationships.
RESEARCH ARTICLES
Biomechanical and morphological determinants of maximal jumping performance in callitrichine monkeys
Summary: Interspecific variation in jumping ability among callitrichine monkeys depends on both anatomical and behavioral adaptations to enhance performance.
Getting slimmer without dieting or exercising: zebra finches can rapidly lose mass while maintaining food intake and decreasing activity
Highlighted Article: Birds are able to regulate body mass while maintaining dietary intake and reducing overall activity.
HIF signaling in the prothoracic gland regulates growth and development in hypoxia but not normoxia in Drosophila
Highlighted Article: Presentation of evidence against the hypothesis that functional hypoxia triggers molting in Drosophila. However, in hypoxia, prothoracic HIF signaling plays a beneficial role in speeding development.
Dynamic soaring decouples dynamic body acceleration and energetics in albatrosses
Summary: Understanding fine-scale energetics in relation to the flight mechanics of soaring birds requires an evaluation of costs that come from both dynamic movements and rotation.
Phototaxis is a satiety-dependent behavioral sequence in Hydra vulgaris
Summary: Phototaxis in Hydra vulgaris is satiety dependent, driven by specific changes in behavior.
Light sensitivity of the circadian system in the social Highveld mole-rat Cryptomys hottentotus pretoriae
Summary: Day-time light suppresses locomotor activity of Highveld mole-rats in a dose-dependent manner, confirming that this species has a higher threshold for light responsiveness compared with aboveground rodents.
Include the females: morphology–performance relationships vary between sexes in lizards
Summary: Selective pressures might shape males and females differently, with implications for the functional relevance of sexual dimorphism.
The functional role of the rabbit digastric muscle during mastication
Summary: Analysis of digastric muscle function during mastication provides some support for a link between spindle abundance and muscle function: muscles that absorb a relatively large amount of negative work have a low spindle abundance.
Torpor energetics are related to the interaction between body mass and climate in bats of the family Vespertilionidae
Summary: Smaller vespertilionid bats enter torpor at higher ambient temperature and reach lower minimum torpid metabolic rate compared with their larger counterparts, favoring torpor expression by larger bats in colder sites and by smaller bats in warmer sites.
Stable isotopes reveal sex- and context-dependent amino acid routing in green anole lizards (Anolis carolinensis)
Highlighted Article: Stable isotope analysis of essential amino acid routing with increased activity and diet restriction in green anole lizards shows increased allocation to liver and spleen, rather than muscle, likely for metabolic fuel and blood cell turnover.
Functioning of unidirectional ventilation in flying hawkmoths evaluated by pressure and oxygen measurements and X-ray video and tomography
Editor's choice: Longitudinal flight muscles are attached to the movable vertical mesophragm, providing sucking force in the air sacs behind for unidirectional ventilation.
Neuromodulator-induced temperature robustness in a motor pattern: a comparative study between two decapod crustaceans
Summary: The release of neuropeptide from modulatory projection neurons plays a crucial role in maintaining neuron and circuit function at elevated temperatures across crustacean species.
Fat body lipogenic capacity in honey bee workers is affected by age, social role and dietary protein
Summary: Honey bee workers show reduced fat synthesis capacity as they age and leave the nest to forage. Young bees deprived of protein have low, forager-like fat synthesis capacity.
ECR SPOTLIGHTS
Harnessing physiological research for smarter environmental policy

In their Perspective, Alexia Dubuc and colleagues discuss strategies to strengthen collaboration, communication and engagement between physiological researchers and environmental policy makers to ensure that conservation strategies address the threats posed by climate change.
JEB grants to support junior faculty

Learn about the grants that we launched in 2023 to support junior faculty from two of our awardees: Erin Leonard, Early-Career Researcher (ECR) Visiting Fellowship recipient, and Pauline Fleischmann, Research Partnership Kickstart Travel Grant recipient. The next deadline to apply is 28 November 2025.
Early testing could make risky falls a thing of the past for elderly people

Falls cost healthcare systems billions each year, but there may be a solution. Jiaen Wu and colleagues of Stanford University, USA, suggest that measuring the way someone walks before they get old might let doctors know who is at risk for a potentially life-threatening fall in the future.
Meet the JEB team at SEB in Antwerp

JEB is proud to be sponsoring the annual meeting of the Society for Experimental Biology, taking place on 8-11 July in Antwerp, Belgium. Come and introduce yourself at our exhibition stands, at booths 3 and 4 throughout the meeting. Editors Craig Franklin, Katie Gilmour and Sanjay Sane, and Features and Reviews Editor Jarren Kay will be also available for questions at our ‘Meet the Editors’ session from 13:00 – 14:00 in Marble Hall on 8 July, where you can find out about the journal and pick up our exclusive 2025 T-shirt.
Fast & Fair peer review

Our sister journal Biology Open has recently launched the next phase of their Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. To learn more about BiO’s progress and future plans, read the Editorial by Daniel Gorelick, or visit the Fast & Fair peer review page.