Issues

Summary: The first checklist of guidelines for reporting methods of intermittent-flow respirometry to enhance study replicability. Methods reporting for this technique has been inconsistent and incomplete in peer-reviewed articles.

Summary: This Review considers the multiple roles played by Hif-1α in teleosts, examining its involvement in the ventilatory response and cardiac function in hypoxia and its role during thermal disturbance.

Summary: Stearoyl-CoA desaturase 1 loss of function in the fly fat body exacerbates overnutrition-associated pathophysiology, which is rescued by oleic acid supplementation, suggesting a protective role for monounsaturated fatty acids in diet-induced metabolic disease.

Summary: Differently sized Cataglyphis bicolor ants use the same overall locomotion strategy, independent of body size. By contrast, allometrically similar ants of the species Cataglyphis albicans use a clearly different strategy.

Summary: Many species experience oxidative stress and inflammation after repeated activation of the hypothalamic–pituitary–adrenal axis; however, simultaneously fasting and developing elephant seals are resistant to repeated hypothalamic–pituitary–adrenal axis activation.

Highlighted Article: Experimental evidence shows that female Heliconius erato butterflies can discriminate between two ultraviolet (UV) wavelengths, suggesting that the duplicated UV opsin genes in Heliconius function to improve UV color vision.

Summary: Continuous metabolic phenotyping of desert-adapted cactus mice (Peromyscus eremicus) identifies significant metabolic differences between sexes and circadian patterning consistent with lipogenesis and environmental entrainment.

Summary: The head is important for burrowing in caecilians. Although no relationships between push force and skull shape were detected, aquatic species produced lower forces, suggesting adaptations of the locomotor system.

Highlighted Article: Activation of regenerative signaling pathways in the honey bee digestive tract after thermal stress may provide resistance to extreme heat events associated with climate change.

Summary: A method to accurately estimate stance velocity in running that requires only contact time, flight time, average speed and gross anthropometry (i.e. mass and leg length or height), improving generalizability of spring–mass analyses.

Summary: Interneurons of the goldfish retina are resistant to the effects of hypoxia as a result of an intracellular pathway involving ATP-dependent K⁺ channels of the mitochondrial membrane.

Editor's Choice: Soft tissue deformations dissipate substantial energy during human walking, as predicted by a simple dynamic walking model.

Summary: Cardiac Nmnat/NAD⁺/SIR2 pathways are important antagonists of high-fat diet-induced lipotoxic cardiomyopathy and their activation is the key underlying mechanism in the prevention of lipotoxic cardiomyopathy by endurance exercise and cardiac Nmnat overexpression in Drosophila.

Summary: Even very low doses of a simulated infection increase levels of oxidative damage in tree swallow nestlings, but only high doses decrease body mass.

Summary: Integrating morphological analysis of bristled wings seen in miniature insects with physical model experiments shows that aerodynamic forces are unaffected across the broad biological variation in number of bristles.