(1) The time lag for attaining a steady state of 42K movement from blood-side to lumen was 2-4 min.

(2) The flux of 42K was changed as much as 100-fold with but minor effects on the lag time.

(3) The specific activity of the gut did not approach 100% of the blood-side value in this short time although the specific activity of K arriving in the lumen from the transport mechanism must be 100%.

(4) From these results we conclude: I that the K being transported through the gut cannot be mixing with the total cell K of the gut, and therefore II that the route of K transport may be through just the goblet cells, or III that the K may pass through special pathways between or through epithelial cells.

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