The oxygen dissociation curves of the haemoglobin of six species of fish from Uganda, and the effect of 25 mm. Hg of carbon dioxide on them are presented graphically. The fish were selected from habitats varying widely in contents of dissolved oxygen and carbon dioxide. The ecology of these species is correlated with differences in the shape and slope of the curve. Records of fish mortalities in Lakes Albert and Victoria are examined in the light of the new data available and suggestions as to the causes are put forward.

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