This study investigated the effects of high-frequency initial pulses on the efficiency (=total work output/high-energy phosphate consumption) of rat fast skeletal muscle. In situ rat medial gastrocnemius muscles performed 15 repeated shortening contractions (2 s(−1); velocity 50 mm s(−1)) with occluded blood flow while activated with triplets of 400 Hz followed by 60 Hz trains (T400;60) or with constant-frequency trains of either 60 or 91 Hz. All stimulation patterns consisted of six pulses. After the last contraction, the muscles were quickly freeze-clamped and analysed for metabolite levels. The calculated efficiencies were 20.4+/−3.0 mJ micromol(−1)P (N=7), 19.4+/−1.8 mJ micromol(−1)P (N=8) and 19.6+/−2.5 mJ micromol(−1)P (N=7; means +/− s.d.) for T400;60, 60 and 91 Hz stimulation respectively (P>0.05). It is concluded that, although high-frequency initial pulses can enhance muscle performance, the efficiency of rat fast skeletal muscle did not differ from that for submaximal constant-frequency stimulation patterns.
JOURNAL ARTICLE|
15 April 2001
High-frequency initial pulses do not affect efficiency in rat fast skeletal muscle
F. Abbate,
F. Abbate
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
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C.J. de Ruiter,
C.J. de Ruiter
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
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A. de Haan
A. de Haan
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
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F. Abbate
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
C.J. de Ruiter
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
A. de Haan
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Van der Boechorststraat 9, The Netherlands. F_Abbate@fbw.vu.nl
Online ISSN: 1477-9145
Print ISSN: 0022-0949
© 2001 by Company of Biologists
2001
J Exp Biol (2001) 204 (8): 1503–1508.
Citation
F. Abbate, C.J. de Ruiter, A. de Haan; High-frequency initial pulses do not affect efficiency in rat fast skeletal muscle. J Exp Biol 15 April 2001; 204 (8): 1503–1508. doi: https://doi.org/10.1242/jeb.204.8.1503
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