1. The effects of variation in the sodium concentration of the bathing media on axonal function has been measured in de-sheathed connectives in the presence of the overlying neural fat-body sheath.

  2. The response to solutions of the same sodium concentration as the haemolymph (15 mM/1) was found to be essentially similar to that recorded in de-sheathed connectives in the absence of the fat-body sheath, there being a rapid decline in amplitude of the recorded action potentials in both preparations.

  3. On the basis of these observations it is concluded that the neural fat-body sheath is unlikely to be involved in the regulation of the extra-neuronal sodium level.

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