Electrophysiological studies on cells of Aplysia central ganglia have become of general interest in recent years and have developed from work on the nature of integrative mechanisms (Arvanitaki & Chalazonitis, 1959; Tauc, 1955; Tauc & Hughes, 1963) to investigations of plastic change at a cellular level (Bruner & Tauc, 1966; Kandel & Tauc, 1965). Earlier work showed the range of phenomena found in a variety of cells, particularly in the abdominal ganglia, but research has now become more concentrated on certain cells which are readily identifiable in all preparations (Strumwasser, 1965 ; Hughes & Tauc, 1961 ; Kandel & Tauc, 1965). Of these cells, the large cell in the right upper quadrant, which is often called the giant cell, or right giant cell (RGC), has been used a great deal in studies on the basic phenomena of spike initiation in molluscan cells (Tauc, 1962). The anatomy of this cell was shown to be quite complex as a result of electrophysiological studies (Hughes & Tauc, 1963) which also revealed the presence of a comparable cell (LGC) on the left side of the C.N.S. Because of similarities in the general pattern of branching of these cells, they were considered homologous.

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I am indebted to Dr Nellie B. Eales for confirming my suspicion that this might not be so and for providing me with a list of distinguishing features.

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