1. A method of integrative flame photometry is described, by which the amount of sodium in biological fluids can be determined, using samples of the order of 10−3 cu.mm.

  2. With pure solutions of sodium chloride, of concentration from 0·05 to 2·0 %, the average error of the method is about 3 % of the concentration.

  3. When other substances are present systematic errors of up to 7·7 % have been recorded.

  4. The possibilities of reducing these systematic errors and of extending the method to deal with other elements are discussed.

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I am indebted to Mr W. T. W. Potts for these analyses.

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