The fascinating diversity in respiratory and circulatory systems across vertebrates is well known to many biologists. Most undergraduate students of animal physiology are familiar with the variety of structures involved in gas exchange in different vertebrate groups, from the water-breathing gills of fish and amphibians to the many distinct forms of air-breathing lungs of terrestrial vertebrates. Equally familiar are the differences in heart structure across vertebrates – from the two-chambered heart of fish to the four-chambered hearts with fully divided ventricles that arose both in mammals and in crocodilians and birds – as well as the corresponding differences in their vascular systems. How these structures work has been a subject of immense interest to many of the great comparative physiologists. Kjell Johansen and Claude Lenfant in particular published a significant number of influential papers throughout the 1960s and 1970s on the structural and functional changes in gas exchange and transport...

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