P. L. Lutz, G. E. Nilsson and H. M. Prentice Kluwer Academic Publishers (2003) pp. 260. ISBN 1-4020-1165-2 €125.00/$138.00/£86.00 (hbk)
The search for the understanding and treatment of hypoxic or ischemic brain injuries is a formidable physiological and biomedical challenge. The lack of effective treatment for these conditions has greatly frustrated medical research: billions of dollars and hundreds of large clinical trials have yielded no significant neuroprotective treatments. A central thesis of Lutz,Nilsson and Prentice's 3rd edition of The Brain Without Oxygen is that a comparative approach to understanding the hypoxic brain may provide new opportunities to solve this problem.
The leading characters of the book are anoxia-tolerant fish, turtles and a few other organisms that possess the capacity to endure long periods of hypoxia and hypothermia. The book compares and contrasts the responses of their brains with that of typical mammals. It describes two main brain survival strategies: a...
