In previous communications (Waddington, 1938; Shen, 1939), it has been shown that a water-soluble derivative of a carcinogenic hydrocarbon is a potent neuralizing agent when implanted with the coagulum of egg albumen into a young gastrula. The present paper describes a similar study with the following modifications: (1) pieces of completely isolated presumptive epidermis were used instead of the whole gastrulae; and (2) the evocatory substance, Na-1:2:5:6-dibenzan-thracene-α-β-endo-succinate, was not tested in the form of a solid implant in admixture with the coagulum of ovoalbumen, but as a solute dissolved in a neutral salt solution in which the epidermal explants were cultivated.

Copyright © 1942 The Company of Biologists Ltd.
1942
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