ABSTRACT
This paper describes two devices for the measurement of colloid osmotic pressure (COP) in volumes of fluid of 0·5 μl or larger. Both devices are based on a design introduced by Hansen (1961) in which COP is measured directly. An ultrafiltration membrane is clamped over a fluid-filled reference chamber which communicates with the sensitive surface of a blood pressure transducer. When colloid-containing fluid is placed on the upper surface of the membrane, fluid is drawn out of the reference chamber, lowering the hydrostatic pressure there. If the membrane is impermeable to the colloid, the pressure drop in the reference chamber is directly proportional to the COP of the colloid-containing fluid.
© 1986 by Company of Biologists
1986
You do not currently have access to this content.