1. Photophores isolated from the mesopelagic fish Argyropelecus hemigymnus consume oxygen at a rate of 1·22± 0·17 nmol min-1 in saline at 20°C.

  2. In the presence of 5 x 10−4moll-1 adrenalin the preparations that responded by a long-lasting luminescence showed a significant decrease of their resting respiration rate. After the adrenalin had been washed out, oxygen consumption increased immediately to the previous resting level and was inhibited by 5 x 10−4moll-1 KCN.

  3. It is suggested that the mechanism of light production by isolated photophores of the epipelagic fish Porichthys and the mesopelagic fish Argyropelecus are different.

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