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Keywords: von Willebrand Factor
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Journal Articles
Journal Articles
J Cell Sci (2017) 130 (21): 3611–3617.
Published: 1 November 2017
... by von Willebrand factor, their most abundant protein, which controls both shape and size of WPBs. WPB are generated in a range of sizes, with the largest granules over ten times the size of the smallest. In this Cell Science at a Glance and the accompanying poster, we discuss the emerging mechanisms...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (17): 2964–2975.
Published: 1 September 2010
... ). Selective and signal-dependent recruitment of membrane proteins to secretory granules formed by heterologously expressed von Willebrand factor . Mol. Biol. Cell 13 , 1582 - 1593 . Cowan A. E. , Olivastro E. M. , Koppel D. E. , Loshon C. A. , Setlow B. , Setlow P...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (1): 19–27.
Published: 1 January 2008
... vary between endothelial tissues, reflecting their differing physiological circumstances. The particular functional demands of the highly multimerised haemostatic protein von Willebrand Factor (VWF), which is stored in WPBs as tubules until release, are responsible for the cigar shape of these granules...
Journal Articles
J Cell Sci (2007) 120 (12): 2117–2125.
Published: 15 June 2007
... of internal striations running parallel to their long axis that are revealed as tubules in transverse section ( Weibel and Palade, 1964 ). These tubules are von Willebrand Factor (VWF), a key haemostatic mediator, which is stored within the organelle ( Wagner et al., 1982 ). We have demonstrated...
Includes: Multimedia, Supplementary data