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Keywords: tyrosine kinase inhibitor
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Journal Articles

Induction of DNA replication by peroxisome proliferators is independent of both tumour necrosis factor α priming and EGF-receptor tyrosine kinase activity

Stephan Chevalier, Neil Macdonald, Ruth A. Roberts
Journal: Journal of Cell Science
J Cell Sci (1999) 112 (24): 4785–4791.
https://doi.org/10.1242/jcs.112.24.4785
Published: 15 December 1999
... upon co-administration of either TNFα or a suboptimal concentration of EGF. Furthermore, there was no gross dysregulation of the CDK and cyclin protein expression profile upon stimulation with nafenopin. Using a specific epidermal growth factor receptor tyrosine kinase inhibitor (4-(3-chloro-4...
View article titled, Induction of DNA replication by peroxisome proliferators is independent of both tumour necrosis factor α priming and EGF-receptor tyrosine kinase activity
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Journal Articles

Morphological polarization of human polymorphonuclear leucocytes in response to three different chemoattractants: an effector response independent of calcium rise and tyrosine kinases

H. Lepidi, Y. Zaffran, J. L. Ansaldi, J. L. Mege, C. Capo
Journal: Journal of Cell Science
J Cell Sci (1995) 108 (4): 1771–1778.
https://doi.org/10.1242/jcs.108.4.1771
Published: 1 April 1995
... distribution, and morphological polarization stimulated by chemoattractants. Downstream effectors may be protein tyrosine kinases. However, the tyrosine kinase inhibitor tyrphostin did not affect the cytoskeletal characteristics elicited by chemoattractants. Taken together, our results suggest...
View article titled, Morphological polarization of human polymorphonuclear leucocytes in response to three different chemoattractants: an effector response independent of calcium rise and tyrosine kinases
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Journal Articles

Cooperative enhancement of hyaluronic acid synthesis by combined use of IGF-I and EGF, and inhibition by tyrosine kinase inhibitor genistein, in cultured mesothelial cells from rabbit pericardial cavity

ATSUSHI HONDA, NAKAE NOGUCHI, HIROMI TAKEHARA, YOSHIAKI OHASHI, NORIKO ASUWA, Y.O. MORI
Journal: Journal of Cell Science
J Cell Sci (1991) 98 (1): 91–98.
https://doi.org/10.1242/jcs.98.1.91
Published: 1 January 1991
... by combined use of IGF-I and EGF could be mediated by a receptor tyrosine kinase-involved transmembrane signaling process that is responsive to IGF-I and EGF. hyaluronic acid synthesis EGF IGF-I tyrosine kinase inhibitor genistein mesothelial cells rabbit pericardium © 1991 by Company...
View article titled, Cooperative enhancement of hyaluronic acid synthesis by combined use of IGF-I and EGF, and inhibition by <span class="search-highlight">tyrosine</span> <span class="search-highlight">kinase</span> <span class="search-highlight">inhibitor</span> genistein, in cultured mesothelial cells from rabbit pericardial cavity