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Keywords: tight junctions
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Journal Articles
In collection:
Adhesion , Polarity
J Cell Sci (2024) 137 (9): jcs261776.
Published: 7 May 2024
...Sandra Citi; Michael Fromm; Mikio Furuse; Lorenza González-Mariscal; Asma Nusrat; Sachiko Tsukita; Jerrold R. Turner ABSTRACT Tight junctions (TJs) are specialized regions of contact between cells of epithelial and endothelial tissues that form selective semipermeable paracellular barriers...
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J Cell Sci (2023) 136 (15): jcs260668.
Published: 8 August 2023
... previously developed a method that we named the zinc-based ultrasensitive microscopic barrier assay (ZnUMBA), which overcomes these limitations, allowing for detection of local tight junction leaks with high spatiotemporal resolution. Here, we present expanded applications for ZnUMBA. ZnUMBA can be used...
Includes: Supplementary data
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J Cell Sci (2013) 126 (17): 3990–3999.
Published: 1 September 2013
...Imogen A. Elsum; Claire Martin; Patrick O. Humbert Summary The crucial role the Crumbs and Par polarity complexes play in tight junction integrity has long been established, however very few studies have investigated the role of the Scribble polarity module. Here, we use MCF10A cells, which fail...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3356–3368.
Published: 1 October 2011
... in polarised epithelial tissues, but its function in these tissues and the relationship with the disorder are unknown. Here we show colocalisation of POF1B with markers of both adherens and tight junctions in human jejunum. The tight junction localisation was maintained by the human POF1B stably expressed...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (16): 2803–2809.
Published: 15 August 2010
... form adherens junctions (AJs) but completely lack tight junctions (TJs) – fully activated SRF. By contrast, AGS gastric adenocarcinoma epithelial cells, which form TJs but are deficient in E-cadherin, and therefore also in AJs, failed to activate SRF. The introduction of wild-type E-cadherin in AGS...
Includes: Supplementary data
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J Cell Sci (2004) 117 (5): 783–798.
Published: 15 February 2004
...Ching-hang Wong; Dolores D. Mruk; Wing-yee Lui; C. Yan Cheng An in vivo model was used to investigate the regulation of tight junction (TJ) dynamics in the testis when adult rats were treated with CdCl 2 . It was shown that the CdCl 2 -induced disruption of the blood-testis barrier (BTB) associated...
Journal Articles
J Cell Sci (2004) 117 (1): 19–29.
Published: 1 January 2004
... enriched at tight junctions. The recent identification of extracellular ligands and intracellular binding proteins for JAMs suggests two functions for JAMs. JAMs associate through their extracellular domains with the leukocyte β2 integrins LFA-1 and Mac-1 as well as with the β1 integrin α4β1. All three...
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