... reactive oxygen species such as superoxide during signalling responses to a variety of extracellular factors. We report here the generation of superoxide as a signalling molecule in early development of Dictyostelium discoideum. Dictyostelium grows as single amoebae but, on starvation, the single cells...

... is sufficient to produce marked proton channel activation under physiological conditions. * Author for correspondence (e-mail: [email protected] ) 22 4 2003 © The Company of Biologists Limited 2003 2003 Membrane potential PKCδ superoxide H + channel NADPH oxidase...

...Toshihiro Kobayashi; John M. Robinson; Harumichi Seguchi ABSTRACT In this study, we show that superoxide production is carried out within intracellular compartments of human neutrophils and not at the plasma membrane following stimulation with phorbol myristate acetate. Oxidant production...

... a considerably high quantum of an active oxyradical species for an extremely short period of time when compared to the pre-hatching (unhatched) and post-hatching (hatched) blastocysts. Hatching could be induced in pre-hatching blastocysts by exposing them to superoxide artificially generated to match...