... in a decreased extent of pol η foci after UV irradiation, indicating that calpain positively regulates pol η accumulation in replication foci. * These authors contributed equally to this work ‡ Author for correspondence ([email protected]) Handling Editor: Maria Carmo-Fonseca...

... in the propagating replication band. We show that it consists of hundreds of replication foci. Post-replicative macronuclear chromatin remains organised in foci. These foci are not randomly distributed throughout the macronucleus, indicating a higher-order organisation of macronuclear chromatin above the level...

..., it is exclusively localised in the nucleus, polκ is found in replication foci in only a small proportion of S-phase cells. It does not colocalise in those foci with proliferating cell nuclear antigen (PCNA) in the majority of cells. This reduced number of cells with polκ foci, when compared with those containing...

...Nicolas Sadoni; M. Cristina Cardoso; Ernst H. K. Stelzer; Heinrich Leonhardt; Daniele Zink DNA replication occurs in mammalian cells at so-called replication foci occupying defined nuclear sites at specific times during S phase. It is an unresolved problem how this specific spatiotemporal...

... was very stable. Foci remained when ∼90% chromatin was removed, suggesting they were attached to an underlying structure. * Author for correspondence 22 01 1993 24 02 1993 © 1993 by Company of Biologists 1993 replication foci DNA polymerase nucleoskeleton dTTP analogues...