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Keywords: receptors
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Journal Articles
J Cell Sci (2011) 124 (1): 19–24.
Published: 01 January 2011
...Balaji Bandyopadhyay; Arum Han; Jinyao Dai; Jianhua Fan; Yong Li; Mei Chen; David T. Woodley; Wei Li TGFβ binding to the TGFβ receptor (TβR) activates R-Smad-dependent pathways, such as Smad2/3, and R-Smad-independent pathways, such as ERK1/2. The mechanism of the TGFβ–TβRII–TβRI–Smad2/3 pathway...
Journal Articles
J Cell Sci (1990) 1990 (Supplement_13): 131–138.
Published: 01 January 1990
... but bind TGFs- β with affinities consistent with the biological potency of the factors. The Type I and Type II binding proteins are glycoproteins with estimated molecular weights of 53 and 73×10 3 M r , respectively. They both bind TGF- β 1 significantly better than TGF- β 2. The Type I receptor has been...