..., and FoxO1 phosphorylation promotes ENaC membrane trafficking by binding to 14-3-3ε in epithelium. Epithelial Na + channel FoxO1 14-3-3ε Protein–protein interaction Protein phosphorylation The epithelial Na + channel (ENaC) localizes to the apical membranes of principal cells...

... to the fine-tuning of the pS4642 level. Cytoskeleton Intermediate filaments Plakin Plectin Protein phosphorylation Among the seven members of the plakin family in mammals ( Sonnenberg and Liem, 2007 ), plectin is one of the best characterized ( Winter and Wiche, 2013 ). Plectin...

... of Biologists Ltd 2013 COPII Secretory pathway ER Protein phosphorylation Cell cycle Chs2p One of the yeast chitin synthases, Chs2p, synthesizes the primary septum which separates mother and daughter cells at the bud-neck late in mitosis. Chs2p is transported to the bud-neck via the secretory...

... Chlamydomonas Cilia and flagella Kinesin-13 Protein phosphorylation Flagellar assembly To learn more about the property of CrKin13 regulated by protein phosphorylation, we examined cellular locations of CrKin13. Phosphorylation of MCAK, a member of kinesin-13 family, has been shown to regulate its...

... pathway. Thus, sphingolipid synthesis and the UPR are coordinately regulated. * Author for correspondence ( [email protected] ) 21 12 2011 © 2012. 2012 ER stress response Endoplasmic reticulum Protein phosphorylation Sphingolipid synthesis Membrane biogenesis during...

... associated with the active formation of PCTV or they could be related to other events in the incubation system, including the formation of protein vesicles. We postulated that, if active vesicle formation was the cause, protein phosphorylation should be reduced if the vesicle-budding reaction were blocked...

... plasticity Synaptic vesicle proteins Protein phosphorylation mRNA microinjection Cell culture Post-tetanic potentiation (PTP) is a widespread form of homosynaptic plasticity that, together with other forms of short-term synaptic enhancement (STE), is considered as one of the neural substrates...

... of Biologists Limited 2006 2006 Arabidopsis Nuclear localization signals Protein phosphorylation pre-mRNA splicing Protein mobility SR protein Advances in fluorescence microscopy, together with expression of proteins tagged to fluorescent reporters, have allowed localization and analysis...

... Limited 2004 2004 Exocytosis Synaptic vesicles Protein kinases Cytoskeleton Protein phosphorylation Invertebrate neurons The synapsins are a family of synaptic vesicle (SV)-associated phosphoproteins involved in the regulation of neurotransmitter release ( Greengard et al., 1993...

... HDACm deacetylates histones H3 and H4, N1/N2 acts as a chaperone for diacetylated H3 and H4 awaiting incorporation into chromatin ( Dilworth et al., 1987 ; Kleinschmidt and Seiter, 1988 ). GST fusion proteins (phosphorylized and not phosphorylized) were immobilized on glutathione-Sepharose 4B...

... Limited 2003 2003 Aurora A Eg2 EDEN-BP Protein phosphorylation MPF RNA deadenylation Calcium oscillations triggered by fertilization stimulate the release of the oocyte from metaphase II (M II) meiotic arrest( Nuccitelli, 1991 ). Calcium induces inactivation of cytostatic factor (CSF...

... 9 2002 © The Company of Biologists Limited 2002 2002 Gastric parietal cell Stomach Rabbit Protein phosphorylation Cytoskeleton cAMP-dependent protein kinase The actin-based cytoskeleton is essential for cellular activities ranging from maintenance of cell morphology...

... telling than the number, however, is the nature of the proteins phosphorylated by CK2 and the functions they play in the cell. Not less than sixty of the known substrates are transcription factors; these, in conjunction with >40 nuclear proteins implicated in gene expression and transcription, a dozen...

... of lasp-1-GST fusion protein fragments with actin further suggests that lasp-1 may interact directly with the actin cytoskeleton ( Schreiber et al., 1998 ). Rabbit cAMP-dependent protein kinase Protein phosphorylation Pancreas Kidney Parotid Parietal cell Chief cell Stomach H + ,K...

...). Together, these results suggest that, during mitosis, a fraction of stathmin, including stathmin phosphorylated on site 16, is concentrated and associated with the mitotic spindle. * Present address: MRC Protein Phosphorylation Unit, Department of Biochemistry, Medical Sciences Institute...

...Gary R. Walker; Charles B. Shuster; David R. Burgess ABSTRACT Research over the past few years has demonstrated the central role of protein phosphorylation in regulating mitosis and the cell cycle. However, little is known about how the mechanisms regulating the entry into mitosis contribute...

... 1997 by Company of Biologists 1997 Protein phosphorylation Microcystin-LR Microfilament Intermediate filament Keratin Desmosome Desmoplakin Ca 2+ /calmodulin-dependent protein kinase cAMPdependent protein kinase Protein phosphorylation has been established as a principal...

...). Approximately 10 μg of mRNA were loaded in each lane. * Author for correspondence (e-mail: [email protected] ) 08 01 1996 05 04 1996 © 1996 by Company of Biologists 1996 Casein kinase 1 Protein kinase Protein phosphorylation Development DNA damage Drosophila...

... USA 19 01 1995 19 03 1996 © 1996 by Company of Biologists 1996 Chromatin Microcystin-LR Mitosis Okadaic acid Protein phosphorylation Histone H1 becomes highly phosphorylated at the onset of mitosis in mammalian cells and is normally dephosphorylated after...

... authors contributed equally to this work 07 12 1995 20 01 1996 © 1996 by Company of Biologists 1996 Vimentin Mitosis Protein phosphorylation In addition to p34 cdc2 kinase, several well-characterized protein kinases such as cAMP-dependent protein kinase and protein...