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Keywords: point mutations
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Journal Articles
Modulation of keratin intermediate filament assembly by single amino acid exchanges in the consensus sequence at the C-terminal end of the rod domain
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (1991) 99 (2): 351–362.
Published: 1 June 1991
...-directed mutagenesis. We produced three mutant keratins, each containing a single point mutation. Tyrosine at position −8 was changed to alanine in keratin K8 (K8Y→A-8) and keratin K18 (KlSY→A-8) and leucine at position −4 was changed to glycine in keratin K18 (K18L→G-4). Mutant keratins were expressed...