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Keywords: pFTY720
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (21): 3878–3887.
Published: 1 November 2015
... with the sphingosine 1-phosphate receptor agonist pFTY720 (fingolimod) (IC50∼100 nM). Psychosine (1 μM, 10 μM) also enhances LPS-induced (EC50∼100 ng/ml) production of pro-inflammatory cytokines in mouse astrocytes, which is also attenuated by pFTY720 (1 μM). Most notably, for the first time, we show that psychosine...
Includes: Supplementary data