...Massimo Negrini; Manuela Ferracin; Silvia Sabbioni; Carlo M. Croce Numerous miRNAs are deregulated in human cancers, and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes. Similarly to cancer genes that encode proteins, deregulation of miRNA-encoding...

... is associated with tyrosine phosphorylation, the signal transduction pathways and the mechanism by which oncogenic tyrosine kinases induce cell growth and neoplastic changes remain elusive ( Jove and Hanafusa, 1987 ; Yarden and Ullrich, 1988 ). The acutely transforming avian sarcoma viruses have been invaluable...

... developmentally controlled, melanocyte-specific products while the other two play a part in melanocyte development. © 1991 by Company of Biologists 1991 colour genes oncogenes melanocytes Pigmentation has long been a favourite and easily used marker in the genetics of diverse organisms...