...José Wojnacki; Gonzalo Quassollo; Martín D. Bordenave; Nicolás Unsain; Gaby F. Martínez; Alan M. Szalai; Olivier Pertz; Gregg G. Gundersen; Francesca Bartolini; Fernando D. Stefani; Alfredo Cáceres; Mariano Bisbal ABSTRACT RhoA plays a crucial role in neuronal polarization, where its action...

... to the molecular mechanisms involved in neuronal polarity and axon elongation is not well understood. In this work, we found that loss of NOX complex function altered neuronal polarization and decreased axonal length by a mechanism that involves actin cytoskeleton dynamics. These results indicate...

... 2014. Published by The Company of Biologists Ltd 2014 Ral Exocyst Par6 Neuroblast migration Neuronal polarity Cell polarization is a key event in neuronal development, controlling neurogenesis ( Farkas and Huttner, 2008 ), neuronal migration and synaptogenesis ( Solecki et al., 2006...

... compartments, which is an essential step during neuronal development. Wee1 is expressed in unpolarized neurons but is downregulated after neurons have extended an axon. Suppression of Wee1 impairs the formation of minor neurites but does not interfere with axon formation. However, neuronal polarity...

... in myelinated axons. J. Neurosci. 28 , 14213 -14222. Horton, A. C. and Ehlers, M. D. ( 2003 ). Neuronal polarity and trafficking. Neuron 40 , 277 -295. Huang, R., He, S., Chen, Z., Dillon, G. H. and Leidenheimer, N. J. ( 2007 ). Mechanisms of homomeric alpha1 glycine receptor endocytosis...

...Giovanna Lalli Neuronal polarization requires localized cytoskeletal changes and polarized membrane traffic. Here, I report that the small GTPase RalA, previously shown to control neurite branching, also regulates neuronal polarity. RalA depletion, or ectopic expression of constitutively active...

... 29 10 2007 © The Company of Biologists Limited 2008 2008 Neuronal polarity Axon Bipolar growth The formation of neurites that occurs immediately after the last mitosis is a crucial event in the development of the brain. In fact, the first neurites support the migration...

...) protein accumulates at the tip of one neurite before and during axon elongation, but global inhibition of GSK-3β leads to APC protein accumulation in all neurites. We conclude that GSK-3β inhibition promotes the development of neuronal polarity, but that this is not mediated by Akt/PKB-dependent...

..., Division of Biochemistry and Molecular Biology, University of California, Berkeley, CA 94720-3202, USA 8 9 2005 © The Company of Biologists Limited 2005 2005 Adenomatous polyposis coli β-Catenin Axon Microtubule Neurite Neuronal polarity During morphogenesis, neurons...

... in antagonizing the asymmetry created by polarized microtubules presenting a uniform minus/plus orientation. * Author for correspondence © 1993 by Company of Biologists 1993 cytoskeleton neuronal polarity axons dendrites We have previously demonstrated that the development of neuronal...

... in determining which of the processes initially extended by hippocampal neurons becomes the definitive axon. * Author for correspondence © The Company of Biologists Limited 1991 1991 hippocampal neurons intracellular organization neuronal polarity axon Golgi complex microtubules...