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Keywords: mutant
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Journal Articles
J Cell Sci (2020) 133 (11): jcs239335.
Published: 11 June 2020
... perinuclear clustering of lysosomes. Importantly, we also characterized a set of novel natural mutations in RNF167-a, which are commonly found in diverse tumor types. We found that RNF167-a-K97N mutant, unlike the wild type, localizes in the cytoplasm and does not promote perinuclear lysosomal clustering...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (12): 2692–2703.
Published: 15 June 2013
... to the cell surface from a recycling compartment. Furthermore, this intracellular pool maintained responsiveness to PKA stimulation with rates similar to WT. These data suggest that new therapeutic targets can be found that would optimize mutant CFTR's stability in the peripheral recycling pathway...
Includes: Supplementary data
Journal Articles
J Cell Sci (2004) 117 (9): 1795–1805.
Published: 01 April 2004
... identified some of the processes involved during sarcomere formation. However, isoform changes during vertebrate muscle development and a lack of mutants have made it difficult to determine how these proteins assemble to form sarcomeres. The indirect flight muscles (IFMs) of Drosophila provide a unique...
Journal Articles
J Cell Sci (1994) 1994 (Supplement_18): 35–42.
Published: 01 January 1994
... evidence for the important role of the Pax genes during embryonic development has been demonstrated by the correlation of mouse developmental mutants and human syndromes with mutations in some Pax genes. To date three Pax genes have been shown to be mutated in undulated, Splotch and small eye...
Journal Articles
J Cell Sci (1991) 99 (1): 57–66.
Published: 01 May 1991
...ETSUKO MUTO; RITSU KAMIYA; SHOICHIRO TSUKITA The in situ organization of the inner dynein arms of Chlamydomonas axonemes was investigated by analyzing a number of tilt-series thin-section electron micrographs taken with improved fixation and staining protocols. The use of mutant axonemes lacking...
Journal Articles
J Cell Sci (1987) 88 (2): 241–250.
Published: 01 September 1987
..., leading to restriction in incor- poration of basal bodies into the developing membranelles. Key words: Paramecium, genetics, development, mutant, oral apparatus. Introduction The oral apparatus is the most prominent organelle of ciliated protozoa, and is of taxonomic, phylogenetic and developmental...