... important proteins required for this process in trypanosomes. Significantly, these are unique and not present in animals, fungi or plants. Trypanosoma Trafficking Clathrin Cytoskeleton Flagellum Evolution Morphology Wellcome Trust 10.13039/100004440 090007/Z/09/Z Medical...

...Kai Murk; Elena M. Blanco Suarez; Louisa M. R. Cockbill; Paul Banks; Jonathan G. Hanley Summary Astrocytes exhibit a complex, branched morphology, allowing them to functionally interact with numerous blood vessels, neighboring glial processes and neuronal elements, including synapses. They also...

... of Biologists Limited 2008 2008 Bcl-2 BCL2 CED-9 DRP-1 Mitochondria Morphology Dynamics Homeostasis C. elegans Transmembrane domain Bcl-2 proteins regulate apoptosis through a mechanism that is sensitive to their expression levels, which vary among Bcl-2 homologs and different tumor...

... with other golgins, TbG63 binds a Golgi Rab GTPase. Fig. 5. Overexpression of TbG63 affects Golgi morphology. (A) Control cells (first row) or those expressing full-length TbG63 tagged with either YFP or BB2 were fixed and labeled for Golgi (GRASP) or TGN (GRIP), and DNA (DAPI). (B) Cells expressing...

... lengthening, primarily by elongating the neck, resulting in longer mushroom-shaped spines. The number of spines and spine head size were not significantly affected by activin treatment. The effects of activin on spinal filamentous actin (F-actin) morphology were independent of protein and RNA synthesis...

...Keith R. Matthews Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which it must adapt either...

...Qin M. Chen; Victoria C. Tu; Jeffrey Catania; Maggi Burton; Olivier Toussaint; Tarrah Dilley ABSTRACT Early passage human diploid fibroblasts develop senescent morphology prematurely within a week after a 2-hour pulse treatment with low or mild dose H 2 O 2 . We test here the role of cell cycle...

...V. L. Johnson; S. C. W. Ko; T. H. Holmstrom; J. E. Eriksson; S. C. Chow ABSTRACT Nuclear morphological changes during apoptosis are very distinct and effector caspases have been implicated to play a central role in these processes. To investigate this in greater detail we examined the effect...

..., melanocyte morphology had evolved from mainly bipolar to dendritic in approxi-mately 66% of cultures. Nle 4 DPhe 7 α-MSH produced dose-related increases in both tyrosinase activity and melanin content although the degree of response was variable and tyrosinase activity was the relatively more responsive...

... do not significantly affect the fibroblastic morphology of the parental spindle cells. In addition, the tumorigenic behavior of these highly malignant cells is not influenced by the ectopic expression of either cadherin. Nevertheless, a fraction of the exogenous cadherins is able to associate...

... systems, however it does not do so until after the development of morphological polarity. Despite this observation, tau very likely has some role in the development of polarity because in cultured cerebellar macroneurons taken from the rat embryonic day 15 primordial cerebellum, the inhibition of tau...

...] and [Mg 2+ ]). The nature of the assembly product was examined using negative staining and thin sectioning electron microscopy. The morphology of the product of assembly of tubulin dimer was found to be strongly influenced by the concentration of glycerol and Mg 2+ in Pipes and Mes buffers; the effects...

... phosphoinositide metabolism vanadate morphology Nearly 25 years ago Nakao and his colleagues ( Nakao, Nakao & Yamazoe, 1960 ; Nakao, Nakao, Yamazoe & Yoshikawa, 1961 ) discovered that ATP was needed to maintain the normal biconcave shape of human red cells. If the ATP content decreased below...