... the years, less is known about the unique structural and functional complexities of the axoneme. Recent work has yielded new insights into the mechanisms by which the axoneme is built with its proper length and architecture, particularly regarding the activity of microtubule-associated proteins (MAPs...

... the microtubule-associated protein (MAP) She1. Evidence suggests that She1 plays a role in polarizing dynein-mediated spindle movements toward the daughter cell; however, how She1 performs this function is unknown. We find that She1 assists dynein in maintaining the spindle in close proximity to the bud neck...

..., axons than seen in control cells. Conversely, Ror overexpression both in non-neuronal cells and in hippocampal neurons resulted in the enhanced extension of short and highly branched processes. These phenotypes were accompanied by changes in the microtubule-associated proteins MAP1B and MAP2. Taken...

...Per Holmfeldt; Goran Brattsand; Martin Gullberg The microtubule-associated protein 4 (MAP4) has recently been shown to counteract destabilization of interphase microtubules caused by catastrophe promotion but not by tubulin sequestering. To address how MAP4 discriminates between destabilization...

...J. Chloë Bulinski; David J. Odde; Bonnie J. Howell; Ted D. Salmon; Clare M. Waterman-Storer Microtubule-associated proteins (MAPs) are proteins that reversibly bind to and regulate microtubule dynamics and functions in vivo. We examined the dynamics of binding of a MAP called ensconsin (E-MAP-115...

... nervous system, although its presence cannot be detected in the cerebral cortices. * Author for correspondence 22 02 1993 01 03 1993 © 1993 by Company of Biologists 1993 MAPs microtubule-associated proteins cytoskeleton peripheral axons Microtubule associated...

... © 1992 The Company of Biologists Ltd. 1992 microtubules microtubule-associated proteins dynamic instability video microscopy Microtubule-associated proteins (MAPs) are a diverse collection of proteins that bind to microtubules. The collection of MAPs includes proteins that act...

... distribution of the MPM-reactive phosphoproteins was determined by examining spindle structures isolated from cells at various stages of mitosis. The susceptibility of the staining pattern to extraction with salt, a procedure known to remove most microtubule-associated proteins (MAPs), was also examined...

... neuroblastoma cell differentiation. © The Company of Biologists Limited 1991 1991 microtubule-associated proteins tau proteins casein kinasell protein kinases neuronal morphogenesis neuronal plasticity neuronal cytoskeleton During brain development, undifferentiated neuroepithelial cells...

... microtubules, has previously been reactivated in vitro . Here, ATP-sensitive microtubule-associated proteins (MAPs) have been isolated from the insect ovaries, and beads coated with such proteins applied to salt-treated, detergent-extracted nutritive tube microtubules microdissected from the insect ovaries...

...Javier Díaz-nido; Jesús Avila ABSTRACT Brain microtubule-associated protein MAP-1 is composed of at least two polypeptides, MAP-1A and MAP-1B, which are among the main components of the neural cytoskeleton. Specific monoclonal and polyclonal antibodies against MAP-1B stain nuclei, mitotic spindles...

... of temperature-dependent assembly and disassembly are composed of tubulin and abundant microtubule-associated proteins. These microtubules are cold- and calcium-labile and assemble at a critical protein concentration of 0 ·11 mg ml −1 at 24°C. The yield of microtubule protein obtained by this new method...