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Keywords: intestine
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Journal Articles
Journal Articles
J Cell Sci (2020) 133 (5): jcs240929.
Published: 13 March 2020
...Thaher Pelaseyed; Gunnar C. Hansson; Ana-Maria Lennon-Duménil ABSTRACT Membrane mucins cover most mucosal surfaces throughout the human body. The intestine harbors complex population of microorganisms (the microbiota) and numerous exogenous molecules that can harm the epithelium. In the colon...
Includes: Supplementary data
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Stem cells
J Cell Sci (2017) 130 (2): 332–343.
Published: 15 January 2017
... modification of heparan sulfate is crucial for regulating Drosophila intestinal stem cell (ISC) division during normal midgut homeostasis and regeneration. Loss of the extracellular heparan sulfate endosulfatase Sulf1 resulted in increased ISC division during normal homeostasis, which was caused...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (14): 3454–3463.
Published: 15 July 2012
...Yannick D. Benoit; Manon B. Lepage; Taoufik Khalfaoui; Éric Tremblay; Nuria Basora; Julie C. Carrier; Lorraine J. Gudas; Jean-François Beaulieu Summary The crypt–villus axis constitutes the functional unit of the small intestine, where mature absorptive cells are confined to the villi, and stem...
Journal Articles
J Cell Sci (2010) 123 (2): 236–245.
Published: 15 January 2010
... small intestine. Here, we demonstrate that PTK6 associates with nuclear and cytoplasmic β-catenin and inhibits β-catenin- and T-cell factor (TCF)-mediated transcription. PTK6 directly phosphorylates β-catenin on Tyr64, Tyr142, Tyr331 and/or Tyr333, with the predominant site being Tyr64. However...
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J Cell Sci (2005) 118 (15): 3289–3304.
Published: 1 August 2005
... of neuronal cells (NG108-15) with subepithelial fibroblasts, we confirmed that mechanically induced Ca 2+ -waves propagated to neurons. From these findings we propose that subepithelial fibroblasts work as a mechanosensor in the intestine. Uptake of food, water and nutrients may cause mechanical stress...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (10): 2077–2086.
Published: 15 April 2004
... of which was prevented by follistatin, was typical of an intestinal wall. Consistent with this interpretation, activin A rapidly induced in the explants the mRNAs for fatty acid binding proteins (FABPs), which are markers of the intestine, but not of the pancreas. We also found that induction of the FABPs...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2002) 115 (23): 4457–4467.
Published: 1 December 2002
... formation. * Author for correspondence (e-mail: lebivic@ibdm.univ-mrs.fr ) 28 8 2002 © The Company of Biologists Limited 2002 2002 Caveolin Epithelia Intestine Golgi Originally defined as non-clathrin-coated flask-shaped plasma membrane invaginations ( Severs, 1988...
Journal Articles
J Cell Sci (2002) 115 (11): 2381–2388.
Published: 1 June 2002
...Christopher S. Potten; Gary Owen; Dawn Booth The stem cells in the crypts of the small intestinal mucosa divide about a thousand times during the lifespan of a laboratory mouse, and yet they show little evidence of any decline in proliferative potential and rarely develop carcinogenic mutations...
Journal Articles
J Cell Sci (2000) 113 (24): 4435–4440.
Published: 15 December 2000
...Wenle Wang; Sergio Uzzau; Simeon E. Goldblum; Alessio Fasano ABSTRACT Intercellular tight junctions are dynamic structures involved in vectorial transport of water and electrolytes across the intestinal epithelium. Zonula occludens toxin derived from Vibrio cholerae interacts with a specific...
Journal Articles
J Cell Sci (2000) 113 (14): 2595–2606.
Published: 15 July 2000
... adulthood and to be predominantly localized at the periphery of a population of large, membrane-bound organelles, called granules, that are seen throughout the early embryo but in later stages are restricted to the cells of the intestine. Analysis of an LMP-1 deficient C. elegans mutant revealed that LMP-1...
Journal Articles
J Cell Sci (1999) 112 (14): 2291–2299.
Published: 15 July 1999
... and milk by the small intestine of the suckling newborn. In both cases apical to basolateral transepithelial transport of IgG is thought to be mediated by FcRn, an IgG Fc receptor with homology to MHC class I antigens. We have now expressed the human FcRn in polarized MDCK cells and analyzed...
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J Cell Sci (1992) 103 (3): 699–708.
Published: 1 November 1992
...S. Heusser; S. Colin; A. Figiel; C. Huet; J.M. Keller; P. Pornet; S. Robine; J. Vandamme; J. Vandekerckhove; M. DAUçA ABSTRACT An actin-binding protein of M r 105,000 has been isolated from anuran amphibian intestinal mucosa. Polyclonal antibodies directed against chicken and pig intestinal villins...