...David P. Thomas; Andrew Sunters; Aleksandra Gentry; Agamemnon E. Grigoriadis ABSTRACT We have investigated the role of c-Fos in chondrocyte differentiation in vitro using both constitutive and inducible overexpression approaches in ATDC5 chondrogenic cells, which undergo a well-defined sequence...

... junctions, arrows indicate continuity between rough and smooth membranes. Bar, 0.5 μ m. Fig. 6. Morphological characteristics of the ER membrane networks formed in vitro from hepatocyte rough and smooth microsomes in the presence of GTP, or in the presence of GTP plus ATP. For clarity...

... sedimentation method. The results presented below support the idea that proliferation of normal gut epithelium ex vivo is initially dependent upon the maintenance of the structural integrity of this tissue and upon factors produced by heterologous mesenchymal cells. Proliferation in vitro was also critically...

...B. J. Cottrell; C. Pye; A. M. Glauert; A. E. Butterworth ABSTRACT Human monocytes were purified from peripheral blood and cultured in vitro on hydrophobic membranes. Such cells developed into mature tissuetype macrophages after approximately 1 week in culture. During this maturation period...

... of the view that these cells are ductal in origin. They are likely to be one of the few cell types that express the basic defect of cystic fibrosis in vitro . The cells may be passaged and sufficient material obtained to permit biochemical and molecular biological analysis. REFERENCES This work...