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Keywords: fibroblasts
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Journal Articles
J Cell Sci (2023) 136 (11): jcs260688.
Published: 8 June 2023
... is not fully understood. Here, we found that primary fibroblasts isolated from aged mice (24 months old) exhibit an increased level of chromosome missegregation and micronucleation compared with that from young mice (2 months old), concomitant with an increased rate of aneuploid cells, suggesting the emergence...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (1): jcs258694.
Published: 12 January 2022
... 11 2021 © 2022. Published by The Company of Biologists Ltd 2022 Summary: Collagen XI, a minor fibrillar collagen, is expressed in mouse corneal stroma during early development and following injury in adults to regulate collagen fibrillogenesis. Regeneration Stroma Fibroblasts...
Includes: Supplementary data
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J Cell Sci (2018) 131 (6): jcs202317.
Published: 26 March 2018
...Qi Sun; Jiao Miao; Jing Luo; Qi Yuan; Hongdi Cao; Weifang Su; Yang Zhou; Lei Jiang; Li Fang; Chunsun Dai; Ke Zen; Junwei Yang ABSTRACT Renal fibrosis is a final common pathway of chronic kidney disease. Sustained activation of fibroblasts is considered to play a key role in perpetuating renal...
Includes: Supplementary data
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Mechanobiology
J Cell Sci (2018) 131 (5): jcs208223.
Published: 6 March 2018
.... Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular clock. Here, we extend this analysis to other tissues and cell types, and identify an inverse relationship between circadian clocks in epithelia and fibroblasts. Epithelial cells from mammary gland, lung and skin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (24): 5610–5625.
Published: 15 December 2013
... predominantly of myogenic cells (CD56 + , desmin + ) and fibroblasts (TE-7 + , collagen VI + , PDGFRα + , vimentin + , fibronectin + ). To evaluate the behaviour of the cell types obtained, we optimised a double immuno-magnetic cell-sorting method for the separation of myogenic cells from fibroblasts...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2005) 118 (19): 4427–4436.
Published: 1 October 2005
... culture. In most situations in vivo, however, matrix assembly occurs within existing three-dimensional (3D) extracellular matrix networks. In an attempt to mimic this environment, we analyzed matrix assembly by fibroblasts cultured on a pre-assembled 3D fibronectin matrix and found significant stimulation...
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Journal Articles
J Cell Sci (2004) 117 (5): 667–675.
Published: 15 February 2004
...J. Michael Sorrell; Arnold I. Caplan Dermal fibroblasts are a dynamic and diverse population of cells whose functions in skin in many respects remain unknown. Normal adult human skin contains at least three distinct subpopulations of fibroblasts, which occupy unique niches in the dermis...
Journal Articles
J Cell Sci (2003) 116 (17): 3471–3478.
Published: 1 September 2003
.... * Author for correspondence (e-mail: [email protected] ) © The Company of Biologists Limited 2003 2003 Chemotaxis Dictyostelium PI 3-kinase Fibroblasts Neutrophils Actin Chemotaxis, movement of a cell towards a chemoattractant signal, is a fundamental process involved in a wide...
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J Cell Sci (1992) 103 (4): 1065–1072.
Published: 1 December 1992
... in proliferating cells and compounds needed for growth activation of arrested cells. By using time-lapse video recording we have studied the possible regulatory role of cholesterol, dolichol and mevalonate in the cell cycle of human diploid fibroblasts (HDF). HDF, which are serum-dependent, were rapidly growth...
Journal Articles
Journal Articles
J Cell Sci (1992) 102 (1): 113–121.
Published: 1 May 1992
... have compared the patterns of RAR expression in human keratinocytes and dermal fibroblasts in vitro , and studied the effects of retinoic acid on RAR expression. RAR-α and RAR-γ were expressed in keratinocytes and fibroblasts: RAR-γ was expressed at similar levels in both cell types but RAR-α was more...