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Keywords: dopamine
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Journal Articles

Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2

Available to Purchase
Sutapa Sinha, Pawan Kumar Vohra, Resham Bhattacharya, Shamit Dutta, Shirshendu Sinha, Debabrata Mukhopadhyay
Journal: Journal of Cell Science
J Cell Sci (2009) 122 (18): 3385–3392.
https://doi.org/10.1242/jcs.053124
Published: 15 September 2009
... pathophysiological outcomes. Our previous studies have shown that the neurotransmitter dopamine could inhibit VEGF-induced phosphorylation of VEGF receptor 2 (VEGFR-2), endothelial cell proliferation, migration, microvascular permeability, and thus, angiogenesis. In this study, we address the mechanism by which...
View articletitled, Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2
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Includes: Supplementary data
Journal Articles

α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

Open Access
Xiangmin M. Peng, Roya Tehranian, Paula Dietrich, Leonidas Stefanis, Ruth G. Perez
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (15): 3523–3530.
https://doi.org/10.1242/jcs.02481
Published: 1 August 2005
... dopamine synthesis by binding to and inhibiting tyrosine hydroxylase, the rate limiting enzyme in dopamine synthesis. Understanding α-synuclein function in dopaminergic cells should add to our knowledge of this key protein, which is implicated in Parkinson's disease and other disorders. Herein, we report...
View articletitled, α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells
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Journal Articles

GSK-3β inhibition/β-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons

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Gonçalo Castelo-Branco, Nina Rawal, Ernest Arenas
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (24): 5731–5737.
https://doi.org/10.1242/jcs.01505
Published: 15 November 2004
...Gonçalo Castelo-Branco; Nina Rawal; Ernest Arenas Wnts are important regulators of dopamine (DA) neuron differentiation in the developing ventral mesencephalon and could thus serve as potential tools in the treatment of Parkinson's disease. In this study, we investigate whether established...
View articletitled, GSK-3β inhibition/β-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons
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