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Keywords: cytoskeleton
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Journal Articles
J Cell Sci jcs.261268.
Published: 19 June 2024
... depend on interactions with the F-actin cytoskeleton that are poorly understood. Here, we show that SET domain protein 3 (SETD3), a recently described actin histidine methyltransferase, directly methylates actin Histidine-73 and enhances F-actin polymerization on mitochondria. SETD3 is a mechano...
Journal Articles
J Cell Sci (2024) 137 (12): jcs262097.
Published: 19 June 2024
... ). The Arabidopsis TONNEAU2 gene encodes a putative novel protein phosphatase 2A regulatory subunit essential for the control of the cortical cytoskeleton . Plant Cell 14 , 833 - 845 . 10.1105/tpc.010402 Drevensek , S. , Goussot , M. , Duroc , Y. , Christodoulidou , A. , Steyaert , S...
Includes: Supplementary data
Journal Articles
J Cell Sci (2024) 137 (8): jcs261919.
Published: 22 April 2024
... cytoskeleton to the ECM and enabling cells to sense matrix rigidity and mount a directional cell migration response to stiffness gradients. Most models studied show preferred migration of single cells or cell clusters towards increasing rigidity. This is referred to as durotaxis, and since its initial...
Journal Articles
J Cell Sci (2024) 137 (3): jcs261740.
Published: 12 February 2024
... involved in the regulation of microtubule dynamics and function in eukaryotes. In the protozoan parasite Trypanosoma brucei , the microtubule cytoskeleton is essential for cell motility and maintaining cell shape. In a previous study, we showed that T. brucei TTLL6A and TTLL12B are required to regulate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2024) 137 (3): jcs260481.
Published: 8 February 2024
... in autophagy contributes to disease. Adaptor proteins Autophagy Cytoskeleton Dynein Kinesin Myosin Jawaharlal Nehru Centre for Advanced Scientific Research http://dx.doi.org/10.13039/501100005116 Science and Engineering Research Board http://dx.doi.org/10.13039/501100001843...
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2024) 137 (2): jcs261389.
Published: 18 January 2024
...Thomas A. Phillips; Stefania Marcotti; Susan Cox; Maddy Parsons ABSTRACT The actin cytoskeleton plays a critical role in cell architecture and the control of fundamental processes including cell division, migration and survival. The dynamics and organisation of F-actin have been widely studied...
Journal Articles
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2023) 136 (19): jcs259448.
Published: 10 October 2023
.... , Viars , F. , Lévy , D. , Bassereau , P. , Bertin , A. and Mangenot , S. ( 2019a ). Septin-based readout of PI(4,5)P2 incorporation into membranes of giant unilamellar vesicles . Cytoskeleton (Hoboken) 76 , 92 - 103 . 10.1002/cm.21480 Beber , A. , Taveneau , C...
Journal Articles
J Cell Sci (2023) 136 (18): jcs261122.
Published: 28 September 2023
.... The mechanism by which paxillin mediated this effect appeared to be through the actin cytoskeleton, which signals to the ERK pathway and induces ECM protein production. These data highlight a novel role for paxillin in HSC biology and fibrosis. * Author for correspondence ( [email protected] ) Handling...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2023) 136 (18): jcs260985.
Published: 25 September 2023
... attributed. Summary: We discuss shear stress in response to fluid dynamics and invite the reader to study shear stress in biological systems, in which shear stress emerges from cell and tissue interactions. Shear stress Fluid shear stress Biomechanics Cytoskeleton European Research...
Journal Articles
J Cell Sci (2023) 136 (17): jcs261301.
Published: 8 September 2023
...) poses an increasing threat to human health. We provide evidence to support a positive correlation between host cell contractility and ZIKV infection efficacy. Cytoskeleton Actomyosin Cell contractility Zika virus Host–pathogen interaction Key Research and Development Program, Ministry...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (16): jcs261356.
Published: 18 August 2023
.... Biophys. Res. Commun. 265 , 112 - 115 . 10.1006/bbrc.1999.1635 Dewane , G. , Salvi , A. M. and Demali , K. A. ( 2021 ). Fueling the cytoskeleton - links between cell metabolism and actin remodeling . J. Cell Sci. 134 , jcs248385 . 10.1242/jcs.248385 Engl , E...
Journal Articles
J Cell Sci (2023) 136 (14): jcs260902.
Published: 24 July 2023
...Mayis Kaba; Amado Carreras-Sureda; Paula Nunes-Hasler; Nicolas Demaurex ABSTRACT Changes in membrane phosphoinositides and local Ca 2+ elevations at sites of particle capture coordinate the dynamic remodeling of the actin cytoskeleton during phagocytosis. Here, we show that the phosphatidylinositol...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Cytoskeleton , Motors
J Cell Sci (2023) 136 (10): jcs261100.
Published: 25 May 2023
..., distribution and reproduction in any medium provided that the original work is properly attributed. Highlighted Article: GIPC3 couples the molecular motors MYO6 and MYO18A to actin cytoskeleton structures in hair cells. GIPC3 is necessary for shaping cuticular plate of the hair cell and hence...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2023) 136 (6): jcs260684.
Published: 20 March 2023
...Ziyi Feng; Zhenfeng Mao; Ziwei Yang; Xiaowei Liu; Fumihiko Nakamura ABSTRACT Filamin A (FLNA) is an actin crosslinking protein that mediates mechanotransduction. External and internal mechanical forces, through the actin cytoskeleton, can induce conformational changes of the FLNA molecule to expose...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (5): jcs260749.
Published: 2 March 2023
.... Published by The Company of Biologists Ltd 2023 Summary: In this Review, we discuss recent studies to highlight what is known about the regulation of endosomal vesicle positioning and transport by motors and cargo adaptors. Cytoskeleton Membrane trafficking Motor proteins Dynein Kinesin...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2022) 135 (22): jcs259769.
Published: 18 November 2022
... the sophisticated force-generation machinery of the cell, the cytoskeleton. All regions of the cell are connected via mechanical linkages, enabling the whole cell to function as a mechanical system. In this Review, we define some of the key concepts of how this machinery functions, highlighting the critical...
Includes: Supplementary data