.... , Korner   R. , Hofmann   K. , Nigg   E. A. ( 2007 ). PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint . Cell   128 , 101 - 114 . Belmont   A. S. ( 2006 ). Mitotic chromosome structure and condensation . Curr. Opin. Cell...

... of whether all S/MAR sequences serve as anchors and whether these anchors are rigid or flexible ( Hancock, 2000 ; Pederson, 2000 ), but this now appears to be reconciled ( Nickerson, 2001 ; Jackson, 2003 ). Chromatin loop Loop anchor S/MAR FISH Gene expression Chromosome structure ©...

..., and the influence of chromosome structural change on their interphase organisation and relative disposition. Sequential silver staining and in situ hybridization with the rDNA probe pTa71, established a correspondence between the expression and organization patterns of rDNA domains in metaphase and interphase cells...

... + , and shown that, crm1 + , which is required for maintenance of higher order chromosome structure, negatively regulates pap1-dependent transcription. In this study, we have characterized a novel gene, pad1 + , which was isolated as a multicopy plasmid capable of confering staurosporine-resistance. We showed...

...) an extensive generation of multinucleated cells was seen. The demethylation was maximal approximately one week after the first subcultivation in the absence of 5-AC. Severe alterations of the chromosome structure were seen after the first subcultivation. During the following weeks the 5-AC-treated cells showed...

... by Company of Biologists 1987 chromosome structure chromosome coiling chromosome decondensation DNA repair inhibition chromatin higher order structure The highly compact nature of metaphase chromosomes imposes severe limitations on the amount of information that can be obtained about...