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Keywords: cell shape
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Journal Articles
J Cell Sci (2022) 135 (20): jcs260042.
Published: 20 October 2022
...Akash Chinchole; Kaisar Ahmad Lone; Shweta Tyagi ABSTRACT Attainment of proper cell shape and the regulation of cell migration are essential processes in the development of an organism. The mixed lineage leukemia (MLL or KMT2A) protein, a histone 3 lysine 4 (H3K4) methyltransferase, plays...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Adhesion , Cytoskeleton
J Cell Sci (2021) 134 (13): jcs258321.
Published: 8 July 2021
...Jean A. Castillo-Badillo; N. Gautam ABSTRACT Cell shape regulation is important, but the mechanisms that govern shape are not fully understood, in part due to limited experimental models in which cell shape changes and underlying molecular processes can be rapidly and non-invasively monitored...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2020) 133 (13): jcs242479.
Published: 3 July 2020
... between directional sensing and polarization . J. Biol. Chem.   278 , 20445 - 20448 . 10.1074/jbc.R300010200 Diz-Muñoz , A. , Fletcher , D. A. and Weiner , O. D. ( 2013 ). Use the force: membrane tension as an organizer of cell shape and motility . Trends Cell Biol.   23 , 47...
Journal Articles
J Cell Sci (2018) 131 (14): jcs186254.
Published: 19 July 2018
...Priyamvada Chugh; Ewa K. Paluch ABSTRACT Precisely controlled cell deformations are key to cell migration, division and tissue morphogenesis, and have been implicated in cell differentiation during development, as well as cancer progression. In animal cells, shape changes are primarily driven...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
J Cell Sci (2018) 131 (6): jcs214015.
Published: 26 March 2018
..., size or membrane curvature, may be probed by intracellular modules, such as the cytoskeleton, reaction–diffusion systems or molecular complexes. In multicellular tissues, cell shape emerges as an important means to transduce tissue-inherent chemical and mechanical cues into intracellular organization...
Journal Articles
Journal Articles
J Cell Sci (2016) 129 (21): 4046–4056.
Published: 1 November 2016
... and reproduction in any medium provided that the original work is properly attributed. Summary: The Rho GTPase Rnd3 is known to alter cell shape and the actin cytoskeleton. Here, the semaphorin receptor plexin-B2 is identified as a new Rnd3 partner that mediates its effects on cell shape. Plexin Rho...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (18): 3375–3383.
Published: 15 September 2016
... and wound repair, cellular unjamming promotes cooperative cellular migration, whereas in cancer invasion, asthma and aberrant wound repair, it unleashes remarkably asocial cellular misbehavior. Cell jamming Cell unjamming Cell shape Collective cellular migration Epithelial cell National...
Journal Articles
J Cell Sci (2012) 125 (13): 3061–3073.
Published: 1 July 2012
.... tension, compression or shear stress), alterations in extracellular matrix (ECM) mechanics and changes in cell shape, are transmitted to the nucleus directly or indirectly to orchestrate transcriptional activities that are crucial for embryogenesis and organogenesis. In this Commentary, we review how...
Journal Articles
J Cell Sci (2011) 124 (24): 4267–4285.
Published: 15 December 2011
... by cell shape and confluence; MTOC off-centering correlates with the polarization of single cells; acto-myosin contractility and microtubule dynamics are required for single-cell polarization; and end binding protein 1 and light intermediate chain 1, but not Par3 and light intermediate chain 2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3356–3368.
Published: 1 October 2011
... that downregulation of claudin-2 might at least contribute to the lack of a TER peak in Mut cells, although the unaffected permeability properties of these cells might suggest that other claudins compensate for the claudin-2 defect. It is known that a regular cell shape (as defined by the polygonal nature...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (4): 555–566.
Published: 15 February 2010
...Hiroyuki Nakajima; Takuji Tanoue Cell-shape change in epithelial structures is fundamental to animal morphogenesis. Recent studies identified myosin-II as the major generator of driving forces for cell-shape changes during morphogenesis. Lulu (Epb41l5) is a major regulator of morphogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (12): 1939–1946.
Published: 15 June 2009
...Sam J. Mathew; Dirk Haubert; Martin Krönke; Maria Leptin Tumour necrosis factor α (TNFα) is a pro-inflammatory mediator with the capacity to induce apoptosis. An integral part of its apoptotic and inflammatory programmes is the control of cell shape through modulation of the cytoskeleton...
Journal Articles
J Cell Sci (2009) 122 (9): 1362–1373.
Published: 1 May 2009
...Thomas J. Widmann; Christian Dahmann Morphogenesis is largely driven by changes in the shape of individual cells. However, how cell shape is regulated in developing animals is not well understood. Here, we show that the onset of TGFβ/Dpp signaling activity correlates with the transition from...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2008) 121 (16): 2625–2628.
Published: 15 August 2008
.... Author for correspondence (e-mail: [email protected] ) 25 6 2008 © The Company of Biologists Limited 2008 2008 Cell shape Integrin Cytoskeleton Membrane recycling Leading lamella Endocytosis Exocytosis Fibroblast Front-to-back model Observation of the shape...
Journal Articles