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1-20 of 192
Keywords: cell migration
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Journal Articles
In collection:
Metabolism
Nioosha Nekooie Marnany, Redouane Fodil, Sophie Féréol, Alwyn Dady, Marine Depp, Frederic Relaix, Roberto Motterlini, Roberta Foresti, Jean-Loup Duband, Sylvie Dufour
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (16): jcs260607.
Published: 15 August 2023
... Competing interests The authors declare no competing or financial interests. 6 9 2022 30 6 2023 © 2023. Published by The Company of Biologists Ltd 2023 Summary: Trunk neural crest cell migration and fate decisions rely on glucose oxidation for energy production...
Includes: Supplementary data
Journal Articles
In collection:
Cell Biology and Disease
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (15): jcs261001.
Published: 9 August 2023
... of activating the SRC promoter in response to TGF-β. JUN, a member of the activator protein (AP)-1 family, localises to the enhancer and regulates TGF-β-induced SRC expression. Furthermore, TGF-β-induced SRC upregulation plays a crucial role in epithelial–mesenchymal transition (EMT)-associated cell migration...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (14): jcs260744.
Published: 27 July 2023
... cells. PhD thesis, Georg-August Universität, Göttingen, Germany . Bodor , D. L. , Pönisch , W. , Endres , R. G. and Paluch , E. K. ( 2020 ). Of cell shapes and motion: the physical basis of animal cell migration . Dev. Cell 52 , 550 - 562 . 10.1016/j.devcel.2020.02.013...
Journal Articles
Nicolas Desjardins-Lecavalier, Matthew G. Annis, Alexander Nowakowski, Alexander Kiepas, Loïc Binan, Joannie Roy, Graziana Modica, Steven Hébert, Claudia L. Kleinman, Peter M. Siegel, Santiago Costantino
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (13): jcs260835.
Published: 4 July 2023
... retain higher migration speed and focal adhesion dynamics over many generations as a result of a motility-related transcriptomic profile. Upregulated genes in isolated fast cells encoded integrin subunits, proto-cadherins and numerous other genes associated with cell migration. Dysregulation of several...
Includes: Supplementary data
Journal Articles
In collection:
Cell Migration
,
Membrane Trafficking
,
Review Commons Transfers
,
Tools in Cell Biology
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
Journal:
Journal of Cell Science
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2023) 136 (12): jcs260468.
Published: 23 June 2023
... a knock-sideways relocalisation approach, we were further able to confirm novel links between Rab11, Rab25 and the ESCPE-1 and retromer multiprotein sorting complexes, and identify new endocytic recycling machinery associated with Rab4, Rab11 and Rab25 that regulates cancer cell migration in the 3D matrix...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (12): jcs260427.
Published: 16 June 2023
... 1 (Az 1 ) in a proteasome-mediated, ubiquitination-independent manner. Az1 absence leads to elevated EPLIN-β levels, causing enhanced cellular migration. Antizyme EPLIN Polyamines Ubiquitin-independent degradation Cell migration National Medical Research Council http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Ignasi Casanellas, Hongkai Jiang, Carolyn M. David, Yolanda Vida, Ezequiel Pérez-Inestrosa, Josep Samitier, Anna Lagunas
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (22): jcs260241.
Published: 21 November 2022
... is limited. In vivo , progenitor cells directionally migrate from the surrounding loose mesenchyme towards regions of increasing matrix adherence (the condensation centers), which is accompanied by the upregulation of fibronectin. Here, we focused on the mechanisms of cell migration during mesenchymal cell...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (20): jcs260042.
Published: 20 October 2022
...Akash Chinchole; Kaisar Ahmad Lone; Shweta Tyagi ABSTRACT Attainment of proper cell shape and the regulation of cell migration are essential processes in the development of an organism. The mixed lineage leukemia (MLL or KMT2A) protein, a histone 3 lysine 4 (H3K4) methyltransferase, plays...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (8): jcs259493.
Published: 3 May 2022
... cell migration . Science 352 , 353 - 358 . 10.1126/science.aad7297 Dubik , N. and Mai , S. ( 2020 ). Lamin A/C: function in normal and tumor cells . Cancers (Basel) 12 , 3688 . 10.3390/cancers12123688 Gong , M. C. , Fuglsang , A. , Alessi , D...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (6): jcs259226.
Published: 14 March 2022
...Jan Faix; Klemens Rottner ABSTRACT The tightly coordinated, spatiotemporal control of actin filament remodeling provides the basis of fundamental cellular processes, such as cell migration and adhesion. Specific protein assemblies, composed of various actin-binding proteins, are thought to operate...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (23): jcs258891.
Published: 9 December 2021
... dynamic remodeling of the actin cytoskeleton. The WASP family verprolin homologous protein (WAVE) is a central Arp2/3 regulator driving lamellipodial protrusions and cell migration in most eukaryotic cells. Together with Abi, NCKAP1/Nap1, CYFIP/Sra-1 and BRK1/HSPC300, WAVE forms a conserved hetero...
Includes: Supplementary data
Journal Articles
Katharina Vestre, Irene Persiconi, Marita Borg Distefano, Nadia Mensali, Noemi Antonella Guadagno, Marine Bretou, Sébastien Wälchli, Catharina Arnold-Schrauf, Oddmund Bakke, Marc Dalod, Ana-Maria Lennon-Dumenil, Cinzia Progida
Journal:
Journal of Cell Science
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (18): jcs259221.
Published: 24 September 2021
... TRPML1 (also known as MCOLN1), enabling the local activation of myosin II at the cell rear. Taken together, our findings identify Rab7b as the missing physical link between lysosomes and the actomyosin cytoskeleton, allowing control of immune cell migration through lysosomal signaling. This article has...
Includes: Supplementary data
Journal Articles
In collection:
Tools in Cell Biology
Yueyang Wang, Alan Y. Hsu, Eric M. Walton, Sung Jun Park, Ramizah Syahirah, Tianqi Wang, Wenqing Zhou, Chang Ding, Abby Pei Lemke, GuangJun Zhang, David M. Tobin, Qing Deng
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (8): jcs258574.
Published: 22 April 2021
... polymerization, cell migration and intracellular signaling. Loss of Rac2 activity leads to defects in neutrophil motility and chemotaxis in zebrafish ( Deng et al., 2011 ; Rosowski et al., 2016 ). However, it remains unknown whether Rac activation is restricted to the front of the cell during neutrophil...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
Zofia Ostrowska-Podhorodecka, Isabel Ding, Wilson Lee, Jelena Tanic, Sevil Abbasi, Pamma D. Arora, Richard S. Liu, Alison E. Patteson, Paul A. Janmey, Christopher A. McCulloch
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (6): jcs254359.
Published: 29 March 2021
...Zofia Ostrowska-Podhorodecka; Isabel Ding; Wilson Lee; Jelena Tanic; Sevil Abbasi; Pamma D. Arora; Richard S. Liu; Alison E. Patteson; Paul A. Janmey; Christopher A. McCulloch ABSTRACT Vimentin is a structural protein that is required for mesenchymal cell migration and directly interacts with actin...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (6): jcs240226.
Published: 22 March 2021
.... and Discher , D. E. ( 2017 ). Mechanosensing by the nucleus: from pathways to scaling relationships . J. Cell Biol. 216 , 305 - 315 . 10.1083/jcb.201610042 Cooper , J. A. ( 2013 ). Mechanisms of cell migration in the nervous system . J. Cell Biol. 202 , 725 - 734 . 10.1083/jcb...
Journal Articles
Kindlin-2 promotes rear focal adhesion disassembly and directional persistence during cell migration
Jie Liu, Zhongzhen Liu, Keng Chen, Wei Chen, Xiyuan Fang, Meng Li, Xuening Zhou, Ning Ding, Huan Lei, Chen Guo, Tao Qian, Yilin Wang, Lin Liu, Yonglong Chen, Hui Zhao, Ying Sun, Yi Deng, Chuanyue Wu
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (1): jcs244616.
Published: 13 January 2021
...Jie Liu; Zhongzhen Liu; Keng Chen; Wei Chen; Xiyuan Fang; Meng Li; Xuening Zhou; Ning Ding; Huan Lei; Chen Guo; Tao Qian; Yilin Wang; Lin Liu; Yonglong Chen; Hui Zhao; Ying Sun; Yi Deng; Chuanyue Wu ABSTRACT Cell migration involves front-to-rear asymmetric focal adhesion (FA) dynamics, which...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (18): jcs243683.
Published: 23 September 2020
...Anna V. Samarelli; Tilman Ziegler; Alexander Meves; Reinhard Fässler; Ralph T. Böttcher ABSTRACT Integrin function depends on the continuous internalization of integrins and their subsequent endosomal recycling to the plasma membrane to drive adhesion dynamics, cell migration and invasion. Here we...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (15): jcs248583.
Published: 5 August 2020
... spectrin binds to ankyrin, and these proteins function to regulate neural development. Cell migration Cytoskeleton Dendrite formation Membrane mechanics Spectrin Neural development The development of the nervous system requires the correct positioning of neurons and the accurate...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
Stephen Kershaw, David J. Morgan, James Boyd, David G. Spiller, Gareth Kitchen, Egor Zindy, Mudassar Iqbal, Magnus Rattray, Christopher M. Sanderson, Andrew Brass, Claus Jorgensen, Tracy Hussell, Laura C. Matthews, David W. Ray
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (11): jcs242842.
Published: 11 June 2020
... (GR, also known as NR3C1) to regulate immunity, energy metabolism and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcription. Here, we show that GCs rapidly inhibit cell migration...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
Laura O'Regan, Giancarlo Barone, Rozita Adib, Chang Gok Woo, Hui Jeong Jeong, Emily L. Richardson, Mark W. Richards, Patricia A. J. Muller, Spencer J. Collis, Dean A. Fennell, Jene Choi, Richard Bayliss, Andrew M. Fry
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (9): jcs241505.
Published: 11 May 2020
... cytoplasmic protrusions and increased cell migration. EML4–ALK V3 also recruits the NEK9 and NEK7 kinases to microtubules via the N-terminal EML4 microtubule-binding region. Overexpression of wild-type EML4, as well as constitutive activation of NEK9, also perturbs cell morphology and accelerates migration...
Includes: Supplementary data
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