... investigated the influence of these chains on cell attachment to substratum,the first step in cell adhesion. Chondroitin sulfate chains did not prevent cell attachment. In fact, a variety of cells attached to chondroitin sulfate,implying the existence of putative receptors and/or binding proteins...

...Amy L. Bodeau; Allison L. Berrier; Anthony M. Mastrangelo; Robert Martinez; Susan E. LaFlamme Cell adhesion is a multistep process that requires the interaction of integrins with their ligands in cell attachment, the activation of integrin-triggered signals, and cell spreading. Integrin β subunit...

... Heparan sulfate proteoglycan Cell attachment Actin cytoskeleton Chinese hamster ovary cell Interactions between extracellular matrix (ECM) molecules and cell surface receptors in vivo regulate various important aspects of cell behavior such as adhesion, proliferation, migration, survival...

... activity of TNfn5. Additional cell attachment studies suggested that both β1 integrins and heparin may differentially influence the attachment of glioma cells to TN fragments. Together, these findings show that C6 glioma cells integrate their response upon binding to at least three domains within TN...

... extracellular matrix substrates in the absence of serum. The antisense oligonucleotide inhibited cell proliferation of anchorage-dependent cells slightly, but there was no effect on cell viability. The effect on cell attachment was similar to that achieved by treating cells with an antisense oligonucleotide...

... 1 repeats and the amino-terminal heparin binding domain were important for stable attachment of G361, HISM and MG-63 cells, but were not involved in keratinocyte attachment. GRGDSP peptide caused near complete inhibition of HISM and MG-63 cell attachment, partially inhibited G361 attachment, but did...

... to fibronectin- or vitronectin-coated surfaces was not affected by microtubule-disrupting agents. * Author for correspondence 10 12 1991 12 06 1991 © 1991 by Company of Biologists 1991 vitronectin cell attachment microtubules epithelial cells demicolcemid cell shape...

... attachment and spreading onto tissue culture plastic was abolished by removal of vitronectin from the serum in the culture medium. These results emphasize that the native structure of collagens is required for serum-enhancement of human endothelial cell attachment and spreading on native collagen types I...