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Keywords: casein kinase
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Journal Articles
J Cell Sci (2010) 123 (17): 2976–2986.
Published: 1 September 2010
...-terminal heterodimerization (PAS) domain of HIF-1α and identify Ser247 as a major site of in vitro modification by casein kinase 1δ (CK1δ). Mutation of this site to alanine, surprisingly, enhanced the transcriptional activity of HIF-1α, a result phenocopied by inhibition or small interfering RNA (siRNA...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1993) 106 (4): 1369–1376.
Published: 1 December 1993
... of these results were confirmed by immunoblots and ELISAs using antibodies to the above protein kinases. In addition to PKA, we found a significant amount of second messenger-independent casein kinase activity ( Fig.6 ) in the sucrose gradient. Like PKA, its activity trailed slightly into the 12 S dynein peak...