... © 2013. Published by The Company of Biologists Ltd 2013 Chemokines Chemokine receptors Osteoclasts Osteoblasts Bone remodelling Bone resorption Calcification Bone-coupling factors Multinucleation Cell fusion Osteolysis Osteopenia Chemokines were originally identified...

... ; maximal production of P i occurs at the time of maximal alkaline phosphatase activity. (iv) BGP-supplemented cultures produce a degree of calcification that corresponds to the amount of BGP conversion to P i . It can be concluded that P i is rate-limiting for the calcification of chondrocyte cultures. BGP...

... of the extracellular matrix. These findings strongly suggest that porous or rough titanium implant surfaces may act like “natural” substrata to permit microscopie tissue/cell ingrowth to improve clinical implant fixation. Fig. 7. Visualization of calcification in calvarial osteoblast cultures plated on glass...

... appear to be deposited within the matrix, thus leading to massive calcification of the nodule. Calcification, as assessed by electron microscopy, histochemical staining and X-ray microprobe analysis, occurred on plastic and collagen substrata in the absence of disodium-βkglycerophosphate. The addition...