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Keywords: cadherins
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Journal Articles
J Cell Sci (2014) 127 (12): 2603–2613.
Published: 15 June 2014
...Tim Pieters; Frans van Roy ABSTRACT Pluripotent embryonic stem cells (ESCs) can self-renew or differentiate into any cell type within an organism. Here, we focus on the roles of cadherins and catenins – their cytoplasmic scaffold proteins – in the fate, maintenance and differentiation of mammalian...
Journal Articles
J Cell Sci (2013) 126 (22): 5293–5304.
Published: 15 November 2013
...Emilie Guillaume; Franck Comunale; Nam Do Khoa; Damien Planchon; Stéphane Bodin; Cécile Gauthier-Rouvière Summary Cadherins are essential in many fundamental processes and assemble at regions of cell–cell contact in large macromolecular complexes named adherens junctions. We have identified...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (10): 2478–2485.
Published: 15 May 2012
...Matthew D. Langer; Huabei Guo; Nitesh Shashikanth; J. Michael Pierce; Deborah E. Leckband We present direct evidence that the N-glycosylation state of neural cadherin impacts the intrinsic kinetics of cadherin-mediated intercellular binding. Micropipette manipulation measurements quantified...
Journal Articles
J Cell Sci (2011) 124 (12): 2013–2020.
Published: 15 June 2011
...Peter J. B. Sabatini; Ming Zhang; Rosalind V. Silverman-Gavrila; Michelle P. Bendeck Cadherins aggregate and stabilize cell–cell junctions through interactions with adjacent cells. In addition, N-cadherin and E-cadherin concentrate at free edges or at the lamellipodia of migrating cells...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (9): 1801–1811.
Published: 1 May 2006
...Samantha J. Stehbens; Andrew D. Paterson; Matthew S. Crampton; Annette M. Shewan; Charles Ferguson; Anna Akhmanova; Robert G. Parton; Alpha S. Yap In contrast to the well-established relationship between cadherins and the actin cytoskeleton, the potential link between cadherins and microtubules...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (1): 66–74.
Published: 1 January 2006
...Porntula Panorchan; Melissa S. Thompson; Kelly J. Davis; Yiider Tseng; Konstantinos Konstantopoulos; Denis Wirtz Cadherins are ubiquitous cell surface molecules that are expressed in virtually all solid tissues and localize at sites of cell-cell contact. Cadherins form a large and diverse family...
Journal Articles
J Cell Sci (2005) 118 (23): 5549–5562.
Published: 1 December 2005
...Juankun Zhang; Martha Betson; Jennifer Erasmus; Kostas Zeikos; Maryse Bailly; Louise P. Cramer; Vania M. M. Braga The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact, the mechanism via which a flat, spread cell shape...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (18): 4325–4339.
Published: 15 August 2004
... and by expressing E-cadherin mutants unable to bind p120. This resulted in defective eye formation and provoked malformations in the craniofacial cartilage structures, derivatives of the cranial neural crest cells. Closer inspection showed that p120 depletion impaired evagination of the optic vesicles and migration...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2003) 116 (24): 4985–4995.
Published: 15 December 2003
... glycoproteins N-cadherin and cadherin-11 [which also occur in heterotypic (`mixed') complexes] are associated with α- and β-catenin, plakoglobin (proportions variable among species), p120 ctn and vinculin. The other complex contains ezrin, periplakin, periaxin and desmoyokin (and so is called the EPPD complex...
Journal Articles
J Cell Sci (2003) 116 (2): 377–386.
Published: 15 January 2003
...Elizabeth E. Robinson; Kathleen M. Zazzali; Siobhan A. Corbett; Ramsey A. Foty Integrins and cadherins are considered to have distinct and opposing functions. Integrins are traditionally cited for their role in cell-substratum interactions, whereas cadherins are thought to mediate strong...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1993) 106 (1): 401–409.
Published: 1 September 1993
...Hiroaki Matsunami; Seiji Miyatani; Takayoshi Inoue; Neal G. Copeland; Debra J. Gilbert; Nancy A. Jenkins; Masatoshi Takeichi ABSTRACT R-cadherin was originally identified as a chicken cad- herin expressed by the retina. Here, we describe the identification of a mouse homologue of R-cadherin. We...
Journal Articles
Journal Articles
J Cell Sci (1993) 105 (4): 993–1000.
Published: 1 August 1993
.... To substantiate the sequence similarity, properties of Armadillo were evaluated for consistency with a junctional role. Armadillo is part of a membrane-associated complex. This complex includes Armadillo, a glycoprotein similar in size to vertebrate cadherins, and the Drosophila homolog of α-catenin. Armadillo co...
Journal Articles
J Cell Sci (1992) 102 (1): 7–17.
Published: 1 May 1992
.... The transmembrane adhesion molecules present in these sites are members of the cadherin family, which are recognized by a pan-cadherin serum, directed against the conserved C terminus of these molecules. Immunoblotting analysis of cultured human endothelial cells using these antibodies revealed three immunoreactive...