1-18 of 18
Keywords: bone
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2024) 137 (16): jcs262202.
Published: 29 August 2024
...-inflammatory phenotype and altering their regulation of angiogenesis, collagen deposition and re-epithelialization during skin wound healing, as well as dampening osteoblast and osteoclast recruitment and bone mineralization during fracture repair. For infected skin wounds, R848-reprogrammed macrophages...
Includes: Supplementary data
Journal Articles
In collection:
Cell migration
J Cell Sci (2021) 134 (9): jcs254979.
Published: 11 May 2021
... fusion between mature OCLs. The R51Q mutation abolishes this regulatory activity, leading to excessive fusion, loss of bone resorption capacity and, consequently, to an osteopetrotic phenotype in vivo . This article has an associated First Person interview with the joint first authors of the paper...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (22): jcs231993.
Published: 14 November 2019
...Ana S. Brandão; Anabela Bensimon-Brito; Raquel Lourenço; Jorge Borbinha; Ana Rosa Soares; Rita Mateus; António Jacinto ABSTRACT Osteoblast differentiation is a key process for bone homeostasis and repair. Multiple signalling pathways have been associated with osteoblast differentiation, yet much...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (21): jcs222737.
Published: 8 November 2018
...Gillian P. Johnson; Elena Stavenschi; Kian F. Eichholz; Michele A. Corrigan; Sean Fair; David A. Hoey ABSTRACT Mechanical loading is a potent stimulus of bone adaptation, requiring the replenishment of the osteoblast from a progenitor population. One such progenitor is the mesenchymal stem cell...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2011) 124 (9): 1465–1476.
Published: 1 May 2011
... of the underlying mechanisms of decreased bone mass and increased fat during aging. We now uncover a new role for the transcription factor Fra-1 in suppressing adipogenesis. Indeed, Fra1 ( Fosl1 ) transgenic ( Fra1 tg) mice, which developed progressive osteosclerosis as a result of accelerated osteoblast...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Lipid biology
J Cell Sci (2004) 117 (3): 441–449.
Published: 22 January 2004
...Jennifer M. Gillette; Sheila M. Nielsen-Preiss While the basic cellular contributions to bone differentiation and mineralization are widely accepted, the regulation of these processes at the intracellular level remains inadequately understood. Our laboratory recently identified annexin 2...
Journal Articles
J Cell Sci (2003) 116 (22): 4587–4596.
Published: 15 November 2003
... and shared significantly reduced longitudinal bone growth. Mutant long bones were characterised by reduced numbers of growth plate chondrocytes and a severe osteoporosis. Decreased JunB levels in epiphysal growth plate chondrocytes and bone lining osteoblasts correlated with deregulated expression of Cyclin...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2000) 113 (3): 377–381.
Published: 1 February 2000
...H. Kalervo Väänänen; Haibo Zhao; Mika Mulari; Jussi M. Halleen ABSTRACT Osteoclasts are multinucleated cells responsible for bone resorption. They have developed an efficient machinery for dissolving crystalline hydroxyapatite and degrading organic bone matrix rich in collagen fibers. When...
Journal Articles
J Cell Sci (1996) 109 (6): 1597–1604.
Published: 1 June 1996
...Eleanor J. Mackie; Susan Ramsey ABSTRACT The extracellular matrix protein tenascin is secreted by osteoblasts but absent from mineralized bone matrix. The current study was undertaken to test the hypothesis that tenascin regulates osteoblast behaviour. Three osteoblast-like cell lines UMR-106, ROS...
Journal Articles
Journal Articles
J Cell Sci (1994) 107 (2): 499–516.
Published: 1 February 1994
...Matthew A. Critchlow; Yvette S. Bland; Doreen E. Ashhurst ABSTRACT Additional bone and cartilage are formed if transforming growth factor-β is injected into the periosteum of calvariae or long bones. To investigate this further, transforming growth factor-β2 was injected into the periosteum...
Journal Articles
J Cell Sci (1993) 105 (1): 61–68.
Published: 1 May 1993
...Geetha Shankar; Ian Davison; Miep H. Helfrich; William T. Mason; Michael A. Horton ABSTRACT Cell-matrix interactions have been shown to play an important role in regulating cell function and behav-iour. In bone, where calcified matrix formation and resorption events are required to be in dynamic...
Journal Articles
J Cell Sci (1993) 104 (4): 1013–1020.
Published: 1 April 1993
...Karen Merry; Robert Dodds; Amanda Littlewood; Maxine Gowen ABSTRACT Over recent years several non-collagenous matrix proteins of bone have been isolated and characterized. One of these proteins, osteopontin, has been shown to be synthesized by osteoblasts and deposited in the bone matrix where...
Journal Articles
J Cell Sci (1990) 1990 (Supplement_13): 149–156.
Published: 1 January 1990
...J. M. Wozney; V. Rosen; M. Byrne; A. J. Celeste; I. Moutsatsos; E. A. Wang ABSTRACT We have approached the study of growth factors affecting cartilage and bone development by investigating those factors present in bone which are able to initiate new cartilage and bone formation in vivo . This has...