.... Author for correspondence (e-mail: [email protected] ) 26 08 1999 09 07 1999 © 1999 by Company of Biologists 1999 Nuclear pore complex Nucleoporin Mitosis Primary biliary cirrhosis Autoantibodies The nuclear pore complex (NPC) is a eukaryotic device that allows...

...Carlos A. Casiano; Göran Landberg; Robert L. Ochs; Eng M. Tan ABSTRACT We have employed human autoantibodies to character-ize a novel cell cycle-regulated nuclear protein, provi-sionally designated p330 d (doublet polypeptide of 330 kDa). The expression and intracellular distribution...

...William S. Saunders; Calvin Chue; Mark Goebl; Carolyn Craig; Robert F. Clark; James A. Powers; Joel C. Eissenberg; Sarah C. R. Elgin; Naomi F. Rothfield; William C. Earnshaw ABSTRACT We have identified a novel autoantibody specificity in scleroderma that we term anti-chromo. These antibodies...

... with this 70K protein can be isolated. One of the many possible explanations for this phenomenon could be that (hn)RNA is involved in the binding of the 70K protein to the Ul RNP particle. Ul RNP nuclear matrix monoclonal antibodies autoantibodies The small nuclear ribonucleoprotein (snRNP...

... nuclear matrix cytoskeleton hnRNP monoclonal antibodies autoantibodies When isolated nuclei are depleted of their membranes, soluble molecules and chromatin by means of subsequent treatments with detergents, nucleases and high-salt solutions, a structural framework, mostly referred...