1-20 of 212
Keywords: adhesion
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2023) 136 (18): jcs261122.
Published: 28 September 2023
..., they are consistent with a previous study showing that focal adhesion kinase (FAK, also known as PTK2, another important FA protein) promotes HSC activation in vitro and liver fibrosis in vivo ( Zhao et al., 2017 ). Given that paxillin and FAK closely interact and are recruited early during FA formation, our...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (8): jcs260576.
Published: 20 April 2023
...-dependent cell–matrix adhesions. Talin forms the mechanical link between the cytoplasmic domain of integrins and the actin cytoskeleton. Through this linkage, talin is at the origin of mechanosignaling occurring at the plasma membrane–cytoskeleton interface. Despite its central position, talin is not able...
Journal Articles
In collection:
Adhesion
J Cell Sci (2022) 135 (23): jcs260232.
Published: 5 December 2022
... and functional differentiation of the gland. Basal mammary epithelial cells (MECs) exhibit remarkable plasticity and progenitor activity that facilitate epithelial expansion. However, their activity must be tightly regulated to restrict excess basal cell activity. Here, we show that adhesion of basal cells...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
J Cell Sci (2022) 135 (9): jcs259579.
Published: 6 May 2022
...Sarah Jacquelyn Smith; Emilie Guillon; Scott A. Holley ABSTRACT The study of how neighboring tissues physically interact with each other, inter-tissue adhesion, is an emerging field at the interface of cell biology, biophysics and developmental biology. Inter-tissue adhesion can be mediated...
Journal Articles
In collection:
Adhesion , Imaging
J Cell Sci (2021) 134 (21): jcs258906.
Published: 10 November 2021
... and plakoglobin, and a highly mobile plakophilin (Pkp2a). As desmosomes mature from Ca 2+ dependence to Ca 2+ -independent hyper-adhesion, their stability increases, but Pkp2a remains highly mobile. We show that desmosome downregulation during growth-factor-induced cell scattering proceeds by internalisation...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
In collection:
Cell migration
J Cell Sci (2021) 134 (7): jcs255653.
Published: 1 April 2021
..., including rolling, adhesion, crawling, diapedesis and sub-endothelial crawling. Nowadays, the role of the endothelium in transmigration is increasingly appreciated. It has been established that leukocyte exit sites on the endothelium and in the pericyte layer are in fact not random but instead may...
Journal Articles
J Cell Sci (2020) 133 (24): jcs247189.
Published: 24 December 2020
... and invasive, cells must downregulate matrix adhesions, which could be a physical marker of invasive potential. We engineered murine astrocytes with common GBM mutations, e.g. Ink4a ( Ink ) or PTEN deletion and expressing a constitutively active EGF receptor truncation (EGFRvIII), to elucidate their effect...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (15): jcs242321.
Published: 12 August 2020
... is the result of two counteracting mechanisms at the cell surface that regulate the degree of elongation: actomyosin, which inhibits cell elongation downstream of RhoA (Rho1 in Drosophila ) and intercellular adhesion, modulated via clathrin-mediated endocytosis of E-cadherin (encoded by shotgun in flies), which...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (13): jcs242974.
Published: 6 July 2020
..., digest and feed on bacteria. It possesses three flotillin-like vacuolins that are strongly associated with membranes and that gradually accumulate on maturing phagosomes. Absence of vacuolins reduced adhesion and particle recognition resulting in a drastic reduction in the uptake of various types...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Adhesion
J Cell Sci (2020) 133 (5): jcs235275.
Published: 2 March 2020
... cytoskeleton and myosins. Myo1e is a long-tailed class I myosin and is highly expressed in B cells, which have not been studied in the context of cell migration. By using intravital microscopy in an in vivo model and performing in vitro experiments, we studied the relevance of Myo1e for the adhesion...
Journal Articles
Journal Articles
In collection:
Adhesion
J Cell Sci (2019) 132 (16): jcs231597.
Published: 15 August 2019
...Rudolf Winklbauer ABSTRACT Cell–cell adhesion strength, measured as tissue surface tension, spans an enormous 1000-fold range when different cell types are compared. However, the examination of basic mechanical principles of cell adhesion indicates that cadherin-based and related mechanisms...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2019) 132 (7): jcs225805.
Published: 5 April 2019
...Bertille Bance; Shailaja Seetharaman; Cécile Leduc; Batiste Boëda; Sandrine Etienne-Manneville ABSTRACT Microtubules play a crucial role in mesenchymal migration by controlling cell polarity and the turnover of cell adhesive structures on the extracellular matrix. The polarized functions...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (21): jcs220814.
Published: 29 October 2018
...% of filopodial tips. Suppression of VASP or Mena (also known as ENAH) reduces filopodial assembly by >75%. However, VASP and Mena do not display consistent filopodial tip localization, but are enriched in focal adhesions (FAs). Interestingly, >85% of FMNL3-containing filopodia are associated with FAs. Two...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (16): jcs215855.
Published: 17 August 2018
...Vibha Singh; Chaitanya Erady; Nagaraj Balasubramanian ABSTRACT Cell-matrix adhesion regulates membrane trafficking controlling anchorage-dependent signaling. While a dynamic Golgi complex can contribute to this pathway, its regulation by adhesion remains unclear. Here we report that loss...
Includes: Supplementary data
Journal Articles