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Keywords: aPKC
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Polarity
J Cell Sci (2020) 133 (22): jcs244830.
Published: 30 November 2020
.../ Highlighted Article: Phosphorylation and dephosphorylation regulate clustering of PAR3, a cell polarity-regulating factor, and this clustering affects the localization of PAR3 and cell–cell junctions. PAR3 PAR-3 ASPP2 aPKC Epithelium Polarity Cell polarity, one of the basic properties...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (16): 2725–2732.
Published: 15 August 2010
... by the unspecific nature of interventions. Here we address this problem in relation to atypical PKC (aPKC) action, which in conjunction with the exocyst complex controls the polarised delivery of promigratory signals. A drug-dependent recruitment approach was employed to manipulate the local recruitment of signals...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2009) 122 (10): 1499–1506.
Published: 15 May 2009
... to unpolarized neurons. Early stages of neuronal polarization are accompanied by increasing levels of interaction of the exocyst complex with PAR-3 and atypical protein kinase C (aPKC), and by the RalA-dependent association of the exocyst complex with PAR-3. Thus, neuronal polarization involves a RalA-regulated...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2008) 121 (15): 2481–2492.
Published: 1 August 2008
...Masaru Kishikawa; Atsushi Suzuki; Shigeo Ohno Atypical protein kinase C (aPKC) generally plays crucial roles in the establishment of cell polarity in various biological contexts. In mammalian epithelial cells, aPKC essentially works towards the transition of primordial spot-like adherens junctions...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (15): 2503–2510.
Published: 1 August 2008
... the truncated Nagie oko protein inactive and recreates all features of the nagie oko mutant phenotype when tested in functional complementation assays. Our observations reveal a previously unknown diversity of alternative multi-protein assembly compositions of the Crumbs–Nagie-oko and Par6-aPKC protein...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (6): 979–987.
Published: 15 March 2006
... that they are part of an evolutionarily conserved PAR-aPKC system involved in cell polarity in various biological contexts. Recent progress has illustrated the common principle that the PAR-aPKC system is the molecular machinery that converts initial polarity cues in the establishment of complementary membrane...
Journal Articles
Journal Articles