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Keywords: Wingless
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Journal Articles
J Cell Sci (2015) 128 (24): 4499–4511.
Published: 15 December 2015
...Eric T. Hall; Esther M. Verheyen ABSTRACT Wnt/Wingless (Wg) and Ras–MAPK signaling both play fundamental roles in growth and cell fate determination, and when dysregulated, can lead to tumorigenesis. Several conflicting modes of interaction between Ras–MAPK and Wnt signaling have been identified in...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (10): 1587–1592.
Published: 15 May 2008
... secretory pathway. By mutating the relevant amino acids, we have investigated how these adducts contribute to the secretion and signalling activity of Wingless, the main Drosophila member of the Wnt family. Analysis of Wingless with a Cysteine 93 to Alanine mutation ([C93A]Wingless) shows that...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (12): 2425–2434.
Published: 15 June 2006
...A. Wodarz; D. B. Stewart; W. J. Nelson; R. Nusse Armadillo, the Drosophila homolog of β-catenin, plays a crucial role in both the Wingless signal transduction pathway and cadherin-mediated cell-cell adhesion, raising the possibility that Wg signaling affects cell adhesion. Here, we use a tissue...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (3): 403–415.
Published: 01 February 2006
... localized during the process. Finally, we define roles for the canonical Wingless and Hedgehog pathways and for core planar cell polarity proteins in denticle polarity. We identified an alternate model in which to examine the signaling and cytoskeletal events of Drosophila PCP: the embryonic denticles...
Includes: Multimedia, Supplementary data