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Keywords: WASp
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Journal Articles
J Cell Sci (2019) 132 (17): jcs233502.
Published: 11 September 2019
... actin assembly by Arp2/3 complex and shares functions with WASp . J. Cell Biol.   151 , 789 - 800 . 10.1083/jcb.151.4.789 Maundrell , K. ( 1990 ). nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine . J. Biol. Chem.   265 , 10857 - 10864 . McMahon...
Includes: Supplementary data
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Lipid Biology
J Cell Sci (2019) 132 (4): jcs219899.
Published: 11 December 2018
.... WASP Cytoskeletal dynamics In vitro reconstitution Supported lipid bilayer Synthetic biology Rapid and controlled modulation of cell shape provides the foundation for cellular functions such as division, growth, migration and adhesion. In eukaryotic cells, much of this modulation can...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (14): 2235–2241.
Published: 15 July 2017
...Olga Alekhina; Ezra Burstein; Daniel D. Billadeau ABSTRACT Proteins of the Wiskott–Aldrich syndrome protein (WASP) family function as nucleation-promoting factors for the ubiquitously expressed Arp2/3 complex, which drives the generation of branched actin filaments. Arp2/3-generated actin regulates...
Includes: Supplementary data
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In collection:
Imaging
J Cell Sci (2017) 130 (8): 1355–1363.
Published: 15 April 2017
... Secretion Branched actin Salivary gland Myosin Drosophila WASp Arp2 Arp3 4D imaging Exocytosis is the process in which cargo that has been synthesized by specialized cells is delivered to the extracellular environment. This type of secretion typically involves the formation of membranous...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (3): 604–620.
Published: 1 February 2016
...Klaus Brinkmann; Moritz Winterhoff; Susanne-Filiz Önel; Jörg Schultz; Jan Faix; Sven Bogdan ABSTRACT Wiskott–Aldrich syndrome proteins (WASPs) are nucleation-promoting factors (NPF) that differentially control the Arp2/3 complex. In Drosophila , three different family members, SCAR (also known...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (18): 4077–4084.
Published: 15 September 2013
... regulator WASp. From in vitro cell biology experiments, and biochemical and structural approaches, we know much about the functional domains of WASp and how WASp might regulate the dynamic actin cytoskeleton downstream of activators such as Cdc42, but in vivo experiments are much more challenging...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (21): 3873–3882.
Published: 1 November 2009
...Athanassios Dovas; Jean-Claude Gevrey; Alberto Grossi; Haein Park; Wassim Abou-Kheir; Dianne Cox Podosomes, adhesion structures capable of matrix degradation, have been linked with the ability of cells to perform chemotaxis and invade tissues. Wiskott-Aldrich Syndrome protein (WASp), an effector...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (19): 3196–3206.
Published: 1 October 2008
...Ana Cvejic; Chris Hall; Magdalena Bak-Maier; Maria Vega Flores; Phil Crosier; Michael J. Redd; Paul Martin Wiskott-Aldrich syndrome protein (WASp) is haematopoietically restricted, and is the causative protein underlying a severe human disorder that can lead to death due to immunodeficiency...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 723–730.
Published: 1 March 2007
... of the relevant actin-regulatory proteins, and significant progress has been made in our understanding of how these proteins choreograph molecular movements associated with T-cell activation. Proteins such as WASp, WAVE2, HS1 and cofilin direct the formation of a cortical actin scaffold at the immune synapse...
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (6): 837–848.
Published: 22 February 2004
...Assel Biyasheva; Tatyana Svitkina; Patricia Kunda; Buzz Baum; Gary Borisy The protrusion of two distinct actin-containing organelles, lamellipodia and filopodia, is thought to be regulated by two parallel pathways: from Rac1 through Scar/WAVEs to lamellipodia, and from Cdc42 through N-WASP...
Journal Articles
J Cell Sci (2003) 116 (2): 239–246.
Published: 15 January 2003
... the driving force behind the formation and elongation. We tried to clarify how signals in response to extracellular cues are transformed to induce filopodial generation and extension. Observations on the formation process of filopodia at growth cones in the neuroblastoma cell line NG108 showed that WAVE (WASP...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2001) 114 (10): 1801–1809.
Published: 15 May 2001
...Tadaomi Takenawa; Hiroaki Miki ABSTRACT Reorganization of cortical actin filaments plays critical roles in cell movement and pattern formation. Recently, the WASP and WAVE family proteins WASP and N-WASP, and WAVE1, WAVE2 and WAVE3 have been shown to regulate cortical actin filament reorganization...
Journal Articles
J Cell Sci (2000) 113 (23): 4165–4176.
Published: 1 December 2000
... and functional regards. Formation of podosomes has been shown to be dependent on the small GTPase CDC42Hs and its effector Wiskott-Aldrich syndrome protein (WASp). In this study, we investigated the functional relation between podosomes and the microtubule system in primary human macrophages. We demonstrate...
Journal Articles