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Keywords: Virus-containing compartment
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Journal Articles
HIV-1 N-myristoylation-dependent hijacking of late endosomes/lysosomes to drive Gag assembly in macrophages
Open AccessGabriel I. Guajardo-Contreras, Ana L. Abdalla, Alex Chen, Meijuan Niu, Erwan Beauchamp, Luc G. Berthiaume, Alan W. Cochrane, Andrew J. Mouland
Journal:
Journal of Cell Science
J Cell Sci (2024) 137 (22): jcs263588.
Published: 21 November 2024
... at intracellular compartments termed virus-containing compartments (VCCs). Our previous research in HeLa cells – in which assembly resembles that found in infected T cells – suggested that late endosomes/lysosomes (LELs) play a role in HIV-1 trafficking towards its assembly sites. However, the role of LELs during...
Includes: Supplementary data