...-independent way, as the extent of apoptosis was not fully restored in virus-infected dKO cells ( Fig. 6 D, lane 8). Nonetheless, HuR does not have a pro-apoptotic role in cell death caused by Dengue virus, VSV and Sendai virus (data not shown), which might be explained by these viruses trigging cytolysis via...

... induced by viruses that exhibit a distinct protein and RNA composition from stress granules, and are associated with translational shut-off and antiviral activities. Virus Stress granule G3BP1 Biotechnology and Biological Sciences Research Council http://dx.doi.org/10.13039/501100000268...

... by immunofluorescence analysis in RNA and DNA virus infections, including those by negative-stranded RNA viruses . J. Virol. 89 , 9383 - 9392 . 10.1128/JVI.01299-15 Strappazzon , F. , Vietri-Rudan , M. , Campello , S. , Nazio , F. , Florenzano , F. , Fimia , G. M. , Piacentini...

... the precise mechanisms vary between different virus families, there are many common themes, including how viruses hijack and repurpose membrane organisation and trafficking, the topic of this Review. Membrane trafficking is a dynamic and versatile process consisting of the interconnected secretory...

... (e.g. RNPs and capsid proteins) carrying NLSs to hijack the host-cell nuclear import machinery or their direct binding to Nups. Among important human viruses that adopt the first strategy are the influenza A virus, whose viral RNP complexes present several NLS motifs ( Martin and Helenius, 1991...

... Myosin Transcription Virus Medical Research Council 10.13039/501100007155 MR/M020606/1 Myosins are actin-based molecular motors that require ATPase activity to cycle through actin attachment and detachment. Myosins can be divided into two subgroups, the conventional myosins, which...

... of the mostly phospholipid bilayers that comprise the membranes. Enveloped viruses offer the experimenter easily purified compartments with well-defined fusion-enabling proteins. Specialized proteins on the viral membrane catalyze the merger of viral and cellular membranes. For influenza virus, fusion between...

... 2018 Summary: In this Cell Science at a Glance article we summarize the current knowledge on the escape of viruses from the endosomal compartment and the cellular detection mechanisms that counteract it. Detection Endosomes Escape Virus Cancer Genomics Center...

... that there is a complex relationship between PTGS and virus infection/resistance. Indeed, viruses can be targets, inducers or inhibitors of PTGS. Introduction of transgenes constitutively expressing part of the genome of a virus can lead to resistance of the plant to infection by this virus (reviewed by Marathe...

..., through the apposing retina, and into the subretinal space. Eyes were injected with 20 μl of 106 plaque-forming units per ml of wild-type influenza virus A (WSN strain) or of VSV (Indiana strain) diluted in infection medium. Proper delivery of viruses into the subretinal space was confirmed...

... lysosome ( Baron et al., 1988 ). Several enveloped viruses have been used to study cellular polarity in epithelial cells, such as in MDCK (Madin-Darby canine kidney) cells, and in neurons. It has been shown that the G-protein of vesicular stomatitis virus (VSV) is sorted only to the basolateral...