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Keywords: Vascular permeability
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Journal Articles
Journal Articles
J Cell Sci (2018) 131 (1): jcs207605.
Published: 10 January 2018
... examined vascular permeability in EC-specific Rap1A- and Rap1B-knockout mice, cell–cell junction remodeling and EC monolayer resistivity in Rap1-deficient ECs under basal, inflammatory or elevated VEGF conditions. Deletion of either Rap1 isoform impaired de novo adherens junction (AJ) formation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (22): 4138–4150.
Published: 15 November 2015
... in endothelium-restricted conditional plectin-knockout mice revealed significant distortions of AJs in stress-prone aortic arch regions and increased pulmonary vascular leakage. Our study opens a new perspective on cytoskeleton-controlled vascular permeability, where a plectin-organized vimentin scaffold keeps...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (9): 1477–1485.
Published: 1 May 2011
... for maintaining the integrity of endothelial cell junctions. * Author for correspondence ( peter.newman@bcw.edu ) 7 1 2011 © 2011. 2011 PECAM-1 CD31 Vascular permeability Adhesion molecules Platelet endothelial cell adhesion molecule (PECAM)-1 (CD31) is a 130 kDa type I...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (24): 4221–4230.
Published: 15 December 2010
... deciphered the roles of CEACAM1 in normal and pathological vascularization. We have found that Ceacam1 −/− mice exhibit a significant increase in basal vascular permeability related to increased basal Akt and endothelial nitric oxide synthase (eNOS) activation in primary murine lung endothelial cells (MLECs...
Includes: Supplementary data
Journal Articles
J Cell Sci (2004) 117 (24): 5905–5912.
Published: 15 November 2004
...Nikolaos A. Tountas; David L. Brautigan Cell migration and retraction are interrelated activities that are crucial for a range of physiological processes such as wound healing and vascular permeability. Immunostaining of brain sections for the specific inhibitor of type-1 protein Ser/Thr...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2001) 114 (7): 1343–1355.
Published: 1 April 2001
... endothelial barrier function, whereas Cdc42 does not affect barrier function. * Author for correspondence (e-mail: anne@ludwig.ucl.ac.uk ) 11 04 2001 © 2001 by Company of Biologists 2001 Vascular permeability Rho GTPase Actin cytoskeleton Tight junction Members of the Rho...
Journal Articles
J Cell Sci (2000) 113 (6): 921–933.
Published: 15 March 2000
... junctional molecule Cell adhesion Vascular permeability The endothelium is extremely important in the regulation of immune responses: both innate immunity and adaptive immune responses depend upon the exit of white blood cells (leukocytes) from the blood and their migration across the endothelium...
Journal Articles
J Cell Sci (1999) 112 (12): 2049–2057.
Published: 15 June 1999
... cells, protecting against hydrogen peroxide and vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) induced increases in permeability with an ED 50 of 0.2-0.5 ng/ml. These newfound abilities of KGF to induce angiogenesis and to stabilize endothelial barriers suggest...