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1-8 of 8
Keywords: Urokinase
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2008) 121 (22): 3747–3756.
Published: 15 November 2008
...Chi-Hui Tang; Marla L. Hill; Alexis N. Brumwell; Harold A. Chapman; Ying Wei The urokinase receptor (uPAR) is upregulated upon tumor cell invasion and correlates with poor lung cancer survival. Although a cis -interaction with integrins has been ascribed to uPAR, whether this interaction alone...
Includes: Supplementary data
Journal Articles
Nelli Shushakova, Natalia Tkachuk, Marc Dangers, Sergey Tkachuk, Joon-Keun Park, Koji Hashimoto, Hermann Haller, Inna Dumler
Journal:
Journal of Cell Science
J Cell Sci (2005) 118 (12): 2743–2753.
Published: 15 June 2005
... functions still remain poorly understood. Here, we show that in MCs, the urokinase-type plasminogen activator (uPA) induces, via its specific receptor (uPAR, CD87), upregulated expression of the complement anaphylatoxin C5a receptor (C5aR, CD88), and modulates C5a-dependent functional responses. This effect...
Journal Articles
Teresa Padró, Rolf M. Mesters, Berno Dankbar, Heike Hintelmann, Ralf Bieker, Michael Kiehl, Wolfgang E. Berdel, Joachim Kienast
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (9): 1961–1971.
Published: 1 May 2002
...Teresa Padró; Rolf M. Mesters; Berno Dankbar; Heike Hintelmann; Ralf Bieker; Michael Kiehl; Wolfgang E. Berdel; Joachim Kienast Emerging data suggest that urokinase-type plasminogen activator (UPA),beyond its role in pericellular proteolysis, may also act as a mitogen. We investigated the function...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (1): 123–134.
Published: 1 January 2000
... of activated ERK and, by this mechanism, regulate cellular migration and invasion. By regulating the uPA/uPAR system, LRP may also regulate ERK activation, cellular migration, and invasion. © 2000 by Company of Biologists 2000 Low density lipoprotein receptor-related protein Urokinase MAP kinase...
Journal Articles
Domenico Ribatti, Daria Leali, Angelo Vacca, Roberta Giuliani, Anna Gualandris, Luisa Roncali, Maria Luisa Nolli, Marco Presta
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (23): 4213–4221.
Published: 1 December 1999
...Domenico Ribatti; Daria Leali; Angelo Vacca; Roberta Giuliani; Anna Gualandris; Luisa Roncali; Maria Luisa Nolli; Marco Presta ABSTRACT In vitro experimental evidences suggest that the proteolytic degradation of the extracellular matrix (ECM) by activation of the urokinase-type plasminogen...
Journal Articles
Irina Mikhailenko, Wayne Considine, Kelley M. Argraves, Dmitri Loukinov, Bradley T. Hyman, Dudley K. Strickland
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (19): 3269–3281.
Published: 1 October 1999
... is responsible for ligand uncoupling within the endosomes. To identify regions responsible for ligand recognition, soluble receptor fragments containing the eight cysteine-rich class A repeats were produced. 125 I-RAP and 125 I-labeled urokinase-type plasminogen activator:plasminogen activator inhibitor type I...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (15): 2597–2606.
Published: 1 August 1999
..., which also inhibit FGF2-mediated upregulation of urokinase-type plasminogen activator (uPA) and in vitro formation of capillary-like structures in three-dimensional type I collagen gel. Various FGF2 mutants originated by deletion or substitution of basic amino acid residues in the amino terminus...
Journal Articles
Sylvie Bonavaud, Cécile Charrière-Bertrand, Christiane Rey, Marie-Pierre Leibovitch, Nina Pedersen, Eric Frisdal, Emmanuelle Planus, Francesco Blasi, Romain Gherardi, Georgia Barlovatz-Meimon
Journal:
Journal of Cell Science
J Cell Sci (1997) 110 (9): 1083–1089.
Published: 1 May 1997
...Sylvie Bonavaud; Cécile Charrière-Bertrand; Christiane Rey; Marie-Pierre Leibovitch; Nina Pedersen; Eric Frisdal; Emmanuelle Planus; Francesco Blasi; Romain Gherardi; Georgia Barlovatz-Meimon ABSTRACT Urokinase can form a tripartite complex binding urokinase receptor (uPAR) and plasminogen...