...- and Golgi-independent manner. Many years later, a number of alternative secretory pathways have been discovered, processes collectively termed unconventional protein secretion (UPS). In the course of these studies, unconventional secretion of FGF2 and IL-1β were found to be based upon distinct pathways...

... responses in TG2-dependent autoimmunity. Transglutaminase Extracellular matrix stabilization Purinergic signaling P2X7 receptor Unconventional protein secretion Innate immunity Unconventional export of cytoplasmic proteins [i.e. the processes by which proteins that do not follow...

...., Kehlenbach, A., Schwappach, B. and Nickel, W. (2004). Unconventional protein secretion: membrane translocation of FGF-2 does not require protein unfolding. J. Cell Sci. 117 , 1727 -1736. Bottomley, S. P., Popplewell, A. G., Scawen, M., Wan, T., Sutton, B. J. and Gore, M. G. (1994). The stability...

...-heidelberg.de 23 5 2007 © The Company of Biologists Limited 2007 2007 Fibroblast growth factor 2 Membrane translocation Unconventional protein secretion Nonclassical export The majority of extracellular proteins are exported from cells through the classical endoplasmic reticulum...

...-mail: [email protected]) 1 12 2003 © The Company of Biologists Limited 2004 2004 Unconventional protein secretion Nonclassical export Fibroblast growth factor FGF-2 Membrane translocation Protein targeting Many examples of protein translocation across membranes...